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+61 3 9035 5621

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Kenneth Myer Building

Staff Directory

Dr Bradley Turner BSc (Hons), PhD (Melb)

Laboratory Head, Motor Neuron Disease Laboratory — Neurodegeneration

Research Papers

Listed below are Dr Bradley Turner's most recent publications.

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Glutathione monoethyl ester prevents TDP-43 pathology in motor neuronal NSC-34 cells

Journal

Neurochemistry International

Volume

Not Found

Begin Page

Date

1/1/N/A

Author(s)

T Chen, BJ Turner, PM Beart, L Sheehan-Hennessy, C Elekwachi, H Muyderman
TDP-43 mutations causing amyotrophic lateral sclerosis are associated with altered expression of RNA-binding protein hnRNP K and affect the Nrf2 antioxidant pathway

Journal

Human Molecular Genetics

Volume

26

Begin Page

1732

Date

1/5/N/A

Author(s)

Diane Moujalled, Alexandra Grubman, Karla Acevedo, Shu Yang, Yazi D Ke, Donia M Moujalled, Clare Duncan, Aphrodite Caragounis, Nirma D Perera, Bradley J Turner, Mercedes Prudencio, Leonard Petrucelli, Ian Blair, Lars M Ittner, Peter J Crouch, Jeffrey R Liddell, Anthony R White
Combination of valproic acid and morpholino splice-switching oligonucleotide produces improved outcomes in spinal muscular atrophy patient-derived fibroblasts

Journal

Neurochemistry International

Volume

108

Begin Page

213

Date

1/9/N/A

Author(s)

Anna Farrelly-Rosch, Chew Ling Lau, Nitin Patil, Bradley J Turner, Fazel Shabanpoor
Synapse Dysfunction of Layer V Pyramidal Neurons Precedes Neurodegeneration in a Mouse Model of TDP-43 Proteinopathies

Journal

Cerebral Cortex

Volume

27

Begin Page

3630

Date

1/7/N/A

Author(s)

Emily E Handley, Kimberley A Pitman, Edgar Dawkins, Kaylene M Young, Rosemary M Clark, Tongcui C Jiang, Bradley J Turner, Tracey C Dickson, Catherine A Blizzard
Inhibition of motor neuron death in vitro and in vivo by a p75 neurotrophin receptor intracellular domain fragment

Journal

Journal Of Cell Science

Volume

129

Begin Page

517

Date

1/2/N/A

Author(s)

Dusan Matusica, Fabienne Alfonsi, Bradley J Turner, Tim J Butler, Stephanie R Shepheard, Mary-Louise Rogers, Sune Skeldal, Clare K Underwood, Marie Mangelsdorf, Elizabeth J Coulson
Emerging Therapies and Challenges in Spinal Muscular Atrophy

Journal

Annals Of Neurology

Volume

81

Begin Page

355

Date

1/3/N/A

Author(s)

Michelle A Farrar, Susanna B Park, Steve Vucic, Kate A Carey, Bradley J Turner, Thomas H Gillingwater, Kathryn J Swoboda, Matthew C Kiernan
AMPK Signalling and Defective Energy Metabolism in Amyotrophic Lateral Sclerosis

Journal

Neurochemical Research

Volume

41

Begin Page

544

Date

1/3/N/A

Author(s)

Nirma D Perera, Bradley J Turner
Enhancing survival motor neuron expression extends lifespan and attenuates neurodegeneration in mutant TDP-43 mice

Journal

Human Molecular Genetics

Volume

25

Begin Page

4080

Date

15/9/N/A

Author(s)

Nirma D Perera, Rebecca K Sheean, Peter J Crouch, Anthony R White, Malcolm K Horne, Bradley J Turner
Disease Mechanisms in ALS: Misfolded SOD1 Transferred Through Exosome-Dependent and Exosome-Independent Pathways

Journal

Cellular And Molecular Neurobiology

Volume

36

Begin Page

377

Date

1/4/N/A

Author(s)

Judith M Silverman, Sarah M Fernando, Leslie I Grad, Andrew F Hill, Bradley J Turner, Justin J Yerbury, Neil R Cashman
The Hippo pathway effector YAP is a critical regulator of skeletal muscle fibre size

Journal

Nature Communications

Volume

6

Begin Page

Date

1/1/N/A

Author(s)

KI Watt, BJ Turner, A Hagg, X Zhang, JR Davey, H Qian, C Beyer, CE Winbanks, KF Harvey, P Gregorevic
Effect of thymic stimulation of CD4+T cell expansion on disease onset and progression in mutant SOD1 mice

Journal

Journal Of Neuroinflammation

Volume

12

Begin Page

Date

27/2/N/A

Author(s)

Rebecca K Sheean, Richard H Weston, Nirma D Perera, Angela D'Amico, Stephen L Nutt, Bradley J Turner
SOD1 protein aggregates stimulate macropinocytosis in neurons to facilitate their propagation

Journal

Molecular Neurodegeneration

Volume

10

Begin Page

Date

31/10/N/A

Author(s)

Rafaa Zeineddine, Jay F Pundavela, Lisa Corcoran, Elise M Stewart, Dzung Do-Ha, Monique Bax, Gilles Guillemin, Kara L Vine, Danny M Hatters, Heath Ecroyd, Christopher M Dobson, Bradley J Turner, Lezanne Ooi, Mark R Wilson, Neil R Cashman, Justin J Yerbury
Characterisation of the stability and bio-functionality of tethered proteins on bioengineered scaffolds: Implications for stem cell biology and tissue repair

Journal

Ifmbe Proceedings

Volume

47

Begin Page

46

Date

1/1/N/A

Author(s)

TY Wang, KAF Bruggeman, RK Sheean, DR Nisbet, CL Parish
Diverse Roles for Wnt7a in Ventral Midbrain Neurogenesis and Dopaminergic Axon Morphogenesis

Journal

Stem Cells And Development

Volume

23

Begin Page

1991

Date

1/9/N/A

Author(s)

Chathurini V Fernando, Julianna Kele, Christopher R Bye, Jonathan C Niclis, Walaa Alsanie, Brette D Blakely, Jan Stenman, Brad J Turner, Clare L Parish
Intercellular propagated misfolding of wild-type Cu/Zn superoxide dismutase occurs via exosome-dependent and -independent mechanisms

Journal

Proceedings Of The National Academy Of Sciences Of The United States Of America

Volume

111

Begin Page

3620

Date

4/3/N/A

Author(s)

Leslie I Grad, Justin J Yerbury, Bradley J Turner, William C Guest, Edward Pokrishevsky, Megan A O'Neill, Anat Yanai, Judith M Silverman, Rafaa Zeineddine, Lisa Corcoran, Janet R Kumita, Leila M Luheshi, Masoud Yousefi, Bradley M Coleman, Andrew F Hill, Steven S Plotkin, Ian R Mackenzie, Neil R Cashman
Misfolded polyglutamine, polyalanine, and superoxide dismutase 1 aggregate via distinct pathways in the cell

Journal

Journal Of Biological Chemistry

Volume

289

Begin Page

6669

Date

7/3/N/A

Author(s)

S Polling, YF Mok, YM Ramdzan, BJ Turner, JJ Yerbury, AF Hill, DM Hatters
Oral treatment with CuII(atsm) increases mutant SOD1 in vivo but protects motor neurons and improves the phenotype of a transgenic mouse model of amyotrophic lateral sclerosis

Journal

Journal Of Neuroscience

Volume

34

Begin Page

8021

Date

1/1/N/A

Author(s)

BR Roberts, NKH Lim, EJ McAllum, PS Donnelly, DJ Hare, PA Doble, BJ Turner, KA Price, SC Lim, BM Paterson, JL Hickey, TW Rhoads, JR Williams, KM Kanninen, LW Hung, JR Liddell, A Grubman, JF Monty, RM Llanos, DR Kramer, JFB Mercer, AI Bush, CL Masters, JA Duce, QX Li, JS Beckman, KJ Barnham, AR White, PJ Crouch
Characterization of the stability and bio-functionality of tethered proteins on bioengineered scaffolds: Implications for stem cell biology and tissue repair

Journal

Journal Of Biological Chemistry

Volume

289

Begin Page

15044

Date

1/1/N/A

Author(s)

TY Wang, KAF Bruggeman, RK Sheean, BJ Turner, DR Nisbet, CL Parish
Overexpression of survival motor neuron improves neuromuscular function and motor neuron survival in mutant SOD1 mice

Journal

Neurobiology Of Aging

Volume

Not Found

Begin Page

15044

Date

N/A

Author(s)

BJ Turner, RK Sheean, MK Horne, N Alfazema, JN Sleigh, KE Davies, K Talbot
Mutant SOD1 inhibits ER-Golgi transport in amyotrophic lateral sclerosis

Journal

Journal Of Neurochemistry

Volume

Not Found

Begin Page

15044

Date

N/A

Author(s)

JD Atkin, MA Farg, KY Soo, AK Walker, M Halloran, BJ Turner, MK Horne, P Nagley
Mutant TDP-43 Deregulates AMPK Activation by PP2A in ALS Models

Journal

Plos One

Volume

9

Begin Page

Date

4/3/N/A

Author(s)

Nirma D Perera, Rebecca K Sheean, John W Scott, Bruce E Kemp, Malcolm K Horne, Bradley J Turner
Genetics of motor neuron disorders: From gene diversity to common cellular conspirators in selective neuronal killing

Journal

Not Found

Volume

Not Found

Begin Page

1

Date

1/6/N/A

Author(s)

RK Sheean, BJ Turner
Motor neuron disease: Causes, classification and treatments

Journal

Not Found

Volume

Not Found

Begin Page

1

Date

1/2/N/A

Author(s)

L Ng, F Khan
Membrane trafficking defects as determinants of motor neuron susceptibility and degeneration in ALS

Journal

Not Found

Volume

Not Found

Begin Page

51

Date

N/A

Author(s)

BJ Turner, Atkin
ALS-Associated TDP-43 Induces Endoplasmic Reticulum Stress, Which Drives Cytoplasmic TDP-43 Accumulation and Stress Granule Formation

Journal

Plos One

Volume

8

Begin Page

Date

29/11/N/A

Author(s)

Adam K Walker, Kai Y Soo, Vinod Sundaramoorthy, Sonam Parakh, Yi Ma, Manal A Farg, Robyn H Wallace, Peter J Crouch, Bradley J Turner, Malcolm K Horne, Julie D Atkin

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Qualifications

Listed below are Dr Bradley Turner's qualifications.
  • PhD
  • BSc (Hons)