Staff Directory

Dr Ben Gu

Research Papers

Listed below are Dr Ben Gu's most recent publications.

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A Thr(357) to Ser polymorphism in homozygous and compound heterozygous subjects causes absent or reduced P2X(7) function and impairs ATP-induced mycobacterial killing by macrophages

Journal

Journal Of Biological Chemistry

Volume

281

Begin Page

2079

Date

27/1/N/A

Author(s)

AN Shemon, R Sluyter, SL Fernando, AL Clarke, LP Dao-Ung, KK Skarratt, BM Saunders, KS Tan, BJ Gu, SJ Fuller, WJ Britton, S Petrou, JS Wiley
Elevated circulating microparticle counts in multiple sclerosis are regulated by platelet P2X7 receptor function

Journal

Multiple Sclerosis Journal

Volume

23

Begin Page

NP19

Date

1/11/N/A

Author(s)

James Wiley, Joelyn Wong, Malgorzata Krupa, Vicky Zhang, Ben Gu, Mark Slee, Jian Teoh
The scavenger activity of the human P2X7 receptor differs from P2X7 pore function by insensitivity to antagonists, genetic variation and sodium concentration: Relevance to inflammatory brain diseases

Journal

Biochimica Et Biophysica Acta-molecular Basis Of Disease

Volume

1864

Begin Page

1051

Date

1/4/N/A

Author(s)

Amber Ou, Ben J Gu, James S Wiley
A systemic view of Alzheimer disease - insights from amyloid-beta metabolism beyond the brain

Journal

Nature Reviews Neurology

Volume

13

Begin Page

612

Date

1/10/N/A

Author(s)

Jun Wang, Ben J Gu, Colin L Masters, Yan-Jiang Wang
Loss of Function of P2X7 Receptor Scavenger Activity in Aging Mice A Novel Model for Investigating the Early Pathogenesis of Age-Related Macular Degeneration

Journal

American Journal Of Pathology

Volume

187

Begin Page

1670

Date

1/8/N/A

Author(s)

Kirstan A Vessey, Ben J Gu, Andrew I Jobling, Joanna A Phipps, Ursula Greferath, Mai X Tran, Michael A Dixon, Paul N Baird, Robyn H Guymer, James S Wiley, Erica L Fletcher
Purinergic receptors P2RX4 and P2RX7 in familial multiple sclerosis

Journal

Human Mutation

Volume

38

Begin Page

736

Date

1/6/N/A

Author(s)

A Dessa Sadovnick, Ben J Gu, Anthony L Traboulsee, Cecily Q Bernales, Mary Encarnacion, Irene M Yee, Maria G Criscuoli, Xin Huang, Amber Ou, Carol J Milligan, Steven Petrou, James S Wiley, Carles Vilarino-Guell
Innate phagocytosis by peripheral blood monocytes is altered in Alzheimer's disease

Journal

Acta Neuropathologica

Volume

132

Begin Page

377

Date

1/9/N/A

Author(s)

Ben J Gu, Xin Huang, Amber Ou, Alan Rembach, Christopher Fowler, Pavan K Avula, Adam Horton, James D Doecke, Victor L Villemagne, S Lance Macaulay, Paul Maruff, Erica L Fletcher, Robyn Guymer, James S Wiley, Colin L Masters
P2X7 IS AN ARCHAIC SCAVENGER RECEPTOR RECOGNIZING APOPTOTIC NEUROBLASTS IN EARLY HUMAN NEUROGENESIS

Journal

Receptors & Clinical Investigation

Volume

Not Found

Begin Page

377

Date

2/5/N/A

Author(s)

Shear stress modulates endothelial KLF2 through activation of P2X4

Journal

Purinergic Signalling

Volume

11

Begin Page

139

Date

1/3/N/A

Author(s)

R Sathanoori, F Rosi, BJ Gu, JS Wiley, CE Mueller, B Olde, D Erlinge
P2X7 receptors mediate innate phagocytosis by human neural precursor cells and neuroblasts

Journal

Stem Cells

Volume

33

Begin Page

526

Date

1/1/N/A

Author(s)

MD Lovelace, BJ Gu, SS Eamegdool, MW Weible, JS Wiley, DG Allen, T Chan-Ling
A 5 ' intronic splice site polymorphism leads to a nulll allele of the P2X(7) gene in 1-2% of the Caucasian population

Journal

Febs Letters

Volume

579

Begin Page

2675

Date

9/5/N/A

Author(s)

KK Skarratt, SJ Fuller, R Sluyter, LP Dao-Ung, BJ Gu, JS Wiley
Genetics of the P2X7 receptor and human disease

Journal

Purinergic Signalling

Volume

5

Begin Page

257

Date

1/6/N/A

Author(s)

Stephen J Fuller, Leanne Stokes, Kristen K Skarratt, Ben J Gu, James S Wiley
Identification of the promoter region of the P2RX4 gene

Journal

Molecular Biology Reports

Volume

37

Begin Page

3369

Date

1/10/N/A

Author(s)

Ben J Gu, Chun Sun, Valentina A Valova, Kristen K Skarratt, James S Wiley
Extracellular ATP dissociates nonmuscle myosin from P2X(7) complex: this dissociation regulates P2X(7) pore formation

Journal

American Journal Of Physiology-cell Physiology

Volume

297

Begin Page

C430

Date

1/8/N/A

Author(s)

Ben J Gu, Catherine Rathsam, Leanne Stokes, Andrew B McGeachie, James S Wiley
Specific detection of non-functional human P2X(7) receptors in HEK293 cells and B-lymphocytes

Journal

Febs Letters

Volume

538

Begin Page

159

Date

13/3/N/A

Author(s)

JA Barden, R Sluyter, BJ Gu, JS Wiley
Rapid ATP-induced release of matrix metalloproteinase 9 is mediated by the P2X(7) receptor

Journal

Blood

Volume

107

Begin Page

4946

Date

15/6/N/A

Author(s)

BJ Gu, JS Wiley
A quantitative method for routine measurement of cell surface P2X(7) receptor function in leucocyte subsets by two-colour time-resolved flow cytometry

Journal

Journal Of Immunological Methods

Volume

325

Begin Page

67

Date

31/8/N/A

Author(s)

Claudia Jursik, Ronald Sluyter, Jennifer G Georgiou, Stephen J Fuller, James S Wiley, Ben J Gu
P2Y(11) receptor expression by human lymphocytes: evidence for two cAMP-linked purinoceptors

Journal

European Journal Of Pharmacology

Volume

426

Begin Page

157

Date

31/8/N/A

Author(s)

AD Conigrave, KC Fernando, B Gu, V Tasevski, WY Zhang, BM Luttrell, JS Wiley
P2X7 receptor cell surface expression and cytolytic pore formation are regulated by a distal C-terminal region

Journal

Journal Of Biological Chemistry

Volume

278

Begin Page

8853

Date

N/A

Author(s)

ML SMART, B GU, R PANCHAL, J WILEY, B CROMER, DA WILLIAMS, S PETROU
Genetic polymorphisms of the human P2X(7) receptor and relationship to function

Journal

Drug Development Research

Volume

53

Begin Page

72

Date

1/6/N/A

Author(s)

JS Wiley, BJ Gu, WY Zhang, RA Worthington, P Dao-Ung, AN Shemon, R Sluyter, S Liang, JA Barden
Impaired transendothelial migration of B-CLL lymphocytes: a defect linked to low L-selectin expression

Journal

Leukemia & Lymphoma

Volume

42

Begin Page

5

Date

1/6/N/A

Author(s)

B Gu, LP Dao, J Wiley
A loss-of-function polymorphic mutation in the cytolytic P2X7 receptor gene and chronic lymphocytic leukaemia: a molecular study

Journal

Lancet

Volume

359

Begin Page

1114

Date

30/3/N/A

Author(s)

JS Wiley, LP Dao-Ung, BJ Gu, R Sluyter, AN Shemon, CP Li, J Taper, J Gallo, A Manoharan
Expression of P2X7 purinoceptors on human lymphocytes and monocytes: Evidence for nonfunctional P2X7 receptors

Journal

American Journal Of Physiology - Cell Physiology

Volume

279

Begin Page

1114

Date

7/12/N/A

Author(s)

BJ Gu, WY Zhang, LJ Bendall, IP Chessell, GN Buell, JS Wiley
P2X(7) Is a Scavenger Receptor for Apoptotic Cells in the Absence of Its Ligand, Extracellular ATP

Journal

Journal Of Immunology

Volume

187

Begin Page

2365

Date

N/A

Author(s)

B Gu, B Saunders, S Petrou, J Wiley

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