Staff Directory

Professor Philip Beart

Division Head — Neurodegeneration

Philip Beart (PhD ANU, DSc Melbourne) has been a NH&MRC Research Fellow for 30 yrs and is currently Professorial Fellow in the Florey Neuroscience Institutes and Adjunct Professor in Pharmacology, University of Melbourne. He worked at the Cambridge and Harvard Universities, before holding positions at the Austin Hospital and Monash University.

Phil's research focus is on brain cell death and homeostatic mechanisms pertinent to neurological diseases. Phil has published >200 papers, served on numerous editorial boards, diverse involvements in learned societies, and trained BSc(Hons)(n=26) and postgraduate (n=30) students. Prizes and lectureships in neuroscience (Bethlehem Griffiths Medal, 2010; Lawrie Austin Lectureship 2009, ANS) and pharmacology (Michael Rand Medal 2009, ASCEPT).

Phil has a long-term commitment to the promotion of medical research, and especially neuroscience, to the wider community and has provided extensive service to the NH&MRC (RF & RGMS User Reference Committees 2010; CDF Committee 2011). Phil is currently Chair of the Promotions Committee (Parkville campus) and President of the International Society for Neurochemistry. Phil has interests in physical fitness, music and cinema, and is a member of the Northcote Yabbies Swimming Club.

Research Papers

Listed below are Professor Philip Beart's most recent publications.

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Galactose-functionalised PCL nanofibre scaffolds to attenuate inflammatory action of astrocytes in vitro and in vivo

Journal

Journal Of Materials Chemistry B

Volume

5

Begin Page

4073

Date

14/6/N/A

Author(s)

Francesca L Maclean, Chew L Lau, Sam Ozergun, Ross D O'Shea, Cecilia Cederfur, Jason Wang, Kevin E Healy, Frederick R Walker, Doris Tomas, Malcolm K Horne, Philip M Beart, David R Nisbet
Analyses of FR127519 and KSG-504 as cholecystokininA receptor antagonists in the rat isolated nodose ganglion

Journal

Pharmacology Reviews And Communications

Volume

9

Begin Page

27

Date

1/12/N/A

Author(s)

PM Beart, E Krstew, RE Widdop
Multiple dopamine receptors-new vistas

Journal

Trends In Pharmacological Sciences

Volume

3

Begin Page

100

Date

1/1/N/A

Author(s)

PM Beart
Regulation of σ‐Receptors: High‐ and Low‐Affinity Agonist States, GTP Shifts, and Up‐Regulation by Rimcazole and 1,3‐Di(2‐Tolyl)guanidine

Journal

Journal Of Neurochemistry

Volume

53

Begin Page

779

Date

1/1/N/A

Author(s)

PM Beart, RD O'Shea, DT Manallack
Excitatory amino acid projections to the periaqueductal gray in the rat: A retrograde transport study utilizing d[3H]aspartate and [3H]GABA

Journal

Neuroscience

Volume

34

Begin Page

163

Date

1/1/N/A

Author(s)

PM Beart, RJ Summers, JA Stephenson, CJ Cook, MJ Christie
Polyamine-sensitive binding of [125I]ifenprodil in washed, frozen-thawed synaptic membranes: Evidence for high affinity binding requiring an open NMDA channel

Journal

Neuroscience Letters

Volume

142

Begin Page

219

Date

17/8/N/A

Author(s)

PM Beart, LD Mercer, EL Conway, AJ Searle
Magnesium ions reveal nanomolar potency of dopamine at [3H]spiperone labelled D-2 receptors in rat corpus striatum

Journal

European Journal Of Pharmacology

Volume

109

Begin Page

417

Date

12/3/N/A

Author(s)

DJ De Vries, PM Beart
An excitatory amino acid projection from ventromedial hypothalamus to periaqueductal gray in the rat: Autoradiographic and electrophysiological evidence

Journal

Neuroscience Letters

Volume

85

Begin Page

205

Date

29/2/N/A

Author(s)

PM Beart, LS Nicolopoulos, DC West, PM Headley
Excitant amino acid projections from rat amygdala and thalamus to nucleus accumbens

Journal

Brain Research Bulletin

Volume

20

Begin Page

467

Date

1/1/N/A

Author(s)

TG Robinson, PM Beart
4-aminotetrolic acid: New conformational-restricted analogue of γ-aminobutyric acid

Journal

Nature New Biology

Volume

234

Begin Page

80

Date

17/11/N/A

Author(s)

PM Beart, DR Curtis, GAR Johnston
ELECTROPHYSIOLOGICAL AND AUTORADIOGRAPHICAL EVIDENCE FOR CHOLECYSTOKININ-A RECEPTORS ON RAT ISOLATED NODOSE GANGLIA

Journal

Journal Of The Autonomic Nervous System

Volume

46

Begin Page

65

Date

1/1/N/A

Author(s)

RE WIDDOP, E KRSTEW, LD MERCER, M CARLBERG, PM BEART, B JARROTT
(S)-5-fluorowillardiine-mediated neurotoxicity in cultured murine cortical neurones occurs via AMPA and kainate receptors

Journal

European Journal Of Pharmacology

Volume

314

Begin Page

249

Date

24/10/N/A

Author(s)

JA Larm, NS Cheung, PM Beart
Up-regulation of rat cortical σ receptors after subchronic administration of rimcazole and 1,3-di(2-tolyl)guanidine

Journal

Neuropharmacology

Volume

27

Begin Page

1201

Date

1/1/N/A

Author(s)

DT Manallack, PM Beart
Analyses of FR127519 and KSG-504 as cholecystokinin(A) receptor antagonists in the rat isolated nodose ganglion

Journal

Pharmacology Communications

Volume

9

Begin Page

27

Date

11/9/N/A

Author(s)

PM Beart, E Krstew, RE Widdop
Erratum: Cyclic voltammetry as an indicator of antioxidant activity (Aust. J. Chem. (2002) 55 (205-212))

Journal

Australian Journal Of Chemistry

Volume

55

Begin Page

27

Date

23/9/N/A

Author(s)

A Papanikos, J Eklund, WR Jackson, VB Kenche, EM Campi, AD Robertson, B Jarrott, PM Beart, FE Munro, JK Callaway
Hippocampal lesions induced by microinjection of the nitric oxide donor nitroprusside

Journal

European Journal Of Pharmacology

Volume

216

Begin Page

331

Date

5/6/N/A

Author(s)

RE Loiacono, PM Beart
COMPETITIVE INHIBITION OF GABA UPTAKE IN RAT BRAIN SLICES BY SOME GABA ANALOGUES OF RESTRICTED CONFORMATION

Journal

Journal Of Neurochemistry

Volume

19

Begin Page

1855

Date

1/1/N/A

Author(s)

PM Beart, GAR Johnston, ML Urn
Type I and II metabotropic glutamate receptor agonists and antagonists evoke cardiovascular effects after intrathecal administration in conscious rats

Journal

British Journal Of Pharmacology

Volume

128

Begin Page

823

Date

9/11/N/A

Author(s)

XC Li, PM Beart, JA Monn, NM Jones, RE Widdop
GABA UPTAKE IN RAT BRAIN SLICES: INHIBITION BY GABA ANALOGUES AND BY VARIOUS DRUGS

Journal

Journal Of Neurochemistry

Volume

20

Begin Page

319

Date

1/1/N/A

Author(s)

PM Beart, GAR Johnston
Evidence for heterogenous glycine domains but conserved multiple states of the excitatory amino acid recognition site of the NMDA receptor: regional binding studies with [3H]glycine and [3H]L-glutamate

Journal

Experimental Brain Research

Volume

86

Begin Page

652

Date

1/9/N/A

Author(s)

RD O'Shea, DT Manallack, EL Conway, LD Mercer, PM Beart
Kainate receptor-mediated apoptosis in primary cultures of cerebellar granule cells is attenuated by mitogen-activated protein and cyclin-dependent kinase inhibitors

Journal

British Journal Of Pharmacology

Volume

135

Begin Page

1733

Date

1/12/N/A

Author(s)

SF Giardina, PM Beart
Receptor site topographies for phencyclidine-like and σ drugs: Predictions from quantitative conformational, electrostatic potential, and radioreceptor analyses

Journal

Molecular Pharmacology

Volume

34

Begin Page

863

Date

1/12/N/A

Author(s)

DT Manallack, MG Wong, M Costa, PR Andrews, PM Beart
Evidence for dopamine receptors on GABA-releasing nerve terminals in rat nucleus accumbens

Journal

British Journal Of Pharmacology

Volume

68

Begin Page

863

Date

1/1/N/A

Author(s)

PM Beart, D Kuppers, WJ Louis
Impairment in T-maze reinforced alternation performance following nucleus basalis magnocellularis lesions in rats

Journal

Behavioural Brain Research

Volume

13

Begin Page

63

Date

1/1/N/A

Author(s)

JD Salamone, PM Beart, JE Alpert, SD Iversen

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