Staff Directory

A/Prof Kevin Barnham

Laboratory Head, Neurotherapeutics Laboratory — Neurodegeneration

Research Papers

Listed below are A/Prof Kevin Barnham's most recent publications.

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A blood-based biomarker panel indicates IL-10 and IL-12/23p40 are jointly associated as predictors of β-amyloid load in an AD cohort

Journal

Scientific Reports

Volume

7

Begin Page

Date

1/12/N/A

Author(s)

S Pedrini, VB Gupta, E Hone, J Doecke, S O'Bryant, I James, AI Bush, CC Rowe, VL Villemagne, D Ames, CL Masters, RN Martins, G Savage, B Wilson, P Bourgeat, J Fripp, S Gibson, H Leroux, S McBride, O Salvado, M Fenech, M Francois, M Barnes, J Baker, K Barnham, S Bellingham, J Bomke, SB Pejoska, R Buckley, L Cheng, S Collins, I Cooke, E Cyarto, D Darby, V Dore, D El-Sheikh, N Faux, C Fowler, K Harrington, A Hill, M Horne, G Jones, A Kamer, N Killeen, H Korrel, F Lamb, N Lautenschlager, K Lennon, QX Li, YY Lim, A Louey, L Macaulay, L Mackintosh, P Maruff, A McIlroy, J Nigro, K Perez, K Pertile, C Restrepo, BR Cardoso, A Rembach, B Roberts, J Robertson, R Rumble, T Ryan, J Sach, B Silbert, C Thai, B Trounson, I Volitakis, M Vovos, L Ward, A Watt, R Williams, M Woodward, P Yates, FY Ugarte, P Zhang, S Bird, B Brown, S Burnham, P Chatterjee, K Cox, S Fernandez, B Fernando, S Gardener, S Laws, F Lim, L Lim, M Tegg, K Lucas, G Martins
A rigorous method to enrich for exosomes from brain tissue.

Journal

J Extracell Vesicles

Volume

6

Begin Page

1348885

Date

N/A

Author(s)

Laura J Vella, Benjamin J Scicluna, Lesley Cheng, Emma G Bawden, Colin L Masters, Ching-Seng Ang, Nicholas Willamson, Catriona McLean, Kevin J Barnham, Andrew F Hill
The novel compound PBT434 prevents iron mediated neurodegeneration and alpha-synuclein toxicity in multiple models of Parkinson's disease

Journal

Acta Neuropathologica Communications

Volume

5

Begin Page

Date

28/6/N/A

Author(s)

David I Finkelstein, Jessica L Billings, Paul A Adlard, Scott Ayton, Amelia Sedjahtera, Colin L Masters, Simon Wilkins, David M Shackleford, Susan A Charman, Wojciech Bal, Izabela A Zawisza, Ewa Kurowska, Andrew L Gundlach, Sheri Ma, Ashley I Bush, Dominic J Hare, Philip A Doble, Simon Crawford, Elisabeth CL Gautier, Jack Parsons, Penny Huggins, Kevin J Barnham, Robert A Cherny
Characterization and Identification of Dityrosine Cross-Linked Peptides Using Tandem Mass Spectrometry

Journal

Analytical Chemistry

Volume

89

Begin Page

6137

Date

6/6/N/A

Author(s)

Soumya Mukherjee, Eugene A Kapp, Amber Lothian, Anne M Roberts, Yury V Vasil'ev, Berin A Boughton, Kevin J Barnham, W Mei Kok, Craig A Hutton, Colin L Masters, Ashley I Bush, Joseph S Beckmann, Somdatta Ghosh Dey, Blaine R Roberts
High Content, Multi-Parameter Analyses in Buccal Cells to Identify Alzheimer's Disease

Journal

Current Alzheimer Research

Volume

13

Begin Page

787

Date

1/1/N/A

Author(s)

Maxime Francois, Michael F Fenech, Philip Thomas, Maryam Hor, Alan Rembach, Ralph N Martins, Stephanie R Rainey-Smith, Colin L Masters, David Ames, Christopher C Rowe, S Lance Macaulay, Andrew F Hill, Wayne R Leifert
Restoration of intestinal function in an MPTP model of Parkinson's Disease

Journal

Scientific Reports

Volume

6

Begin Page

Date

29/7/N/A

Author(s)

LJ Ellett, LW Hung, R Munckton, NA Sherratt, J Culvenor, A Grubman, JB Furness, AR White, DI Finkelstein, KJ Barnham, VA Lawson
Synthesis of Oxorhenium(V) and Oxotechnetium(V) Complexes That Bind to Amyloid-beta Plaques

Journal

Inorganic Chemistry

Volume

55

Begin Page

7944

Date

15/8/N/A

Author(s)

David J Hayne, Jonathan M White, Catriona A McLean, Victor L Villemagne, Kevin J Barnham, Paul S Donnelly
Therapeutically increasing mutant SOD1 metallation status attenuates disease symptoms in an ALS mouse model

Journal

Journal Of Neurochemistry

Volume

123

Begin Page

16

Date

1/10/N/A

Author(s)

N Lim, BR Roberts, PS Donnelly, S Lim, JS Beckman, KJ Barnham, Q Li, AR White, PJ Crouch
THE MOLECULAR MECHANISM OF ACTION FOR METAL-LIGAND COMPLEXES AS POTENTIAL THERAPEUTICS FOR ALZHEIMER'S AND OTHER NEURODEGENERATIVE DISEASES

Journal

Journal Of Neurochemistry

Volume

115

Begin Page

10

Date

1/10/N/A

Author(s)

PJ Crouch, LW Hung, CP Soon, DJ Tew, KA Perez, PA Adlard, A Bush, CL Masters, RA Cherny, QX Li, PS Donnelly, KJ Barnham, AR White
The Glycine Rich Region of the Prion Protein Modulates Uptake of Prion Infectivity

Journal

Prion

Volume

4

Begin Page

190

Date

1/7/N/A

Author(s)

AF Hill, CF Harrison, VA Lawson, CL Masters, R Cappai, KJ Barnham
Novel Metal Ligands Prevent Neuronal Loss and Motor Deficits in Wild Type and Alpha-synuclein Transgenic Mice Treated with 6-Hydroxydopamine Or MPTP

Journal

Movement Disorders

Volume

25

Begin Page

S665

Date

15/9/N/A

Author(s)

RA Cherny, JL George, L Gunawan, N Critch, M Cortes, X Liu, M Nurjono, K Laughton, I Volitakis, J Parsons, KJ Barnham, E Gautier, AI Bush, DI Finkelstein
Modulation of APP and A beta metabolism by metal chelators

Journal

Journal Of Neurochemistry

Volume

94

Begin Page

223

Date

1/8/N/A

Author(s)

AR White, T Du, AF Hill, R Sharples, KJ Barnham, D Holsinger, G Ciccotosto, D Hoke, G Evin, K Laughton, QX Li, I Volitakis, RA Cherny, AI Bush, R Cappai, CL Masters
Methionine oxidation and the toxic principle of the beta-amyloid peptide from Alzheimer's disease

Journal

Journal Of Neurochemistry

Volume

87

Begin Page

99

Date

1/12/N/A

Author(s)

KJ Barnham, GD Ciccotosto, AK Tickler, FE Ali, DG Smith, NA Williamson, YH Lam, D Carrington, D Tew, G Kocak, I Volitakis, F Separovic, CJ Barrow, JD Wade, CL Masters, RA Cherny, CC Curtain, AI Bush, R Cappai
Investigation of the structure of the N-terminal region of prion protein (PrP) via the microwave synthesis of peptide fragments up to 111 amino acids in length

Journal

Journal Of Peptide Science

Volume

14

Begin Page

90

Date

1/8/N/A

Author(s)

Andrew Hill, Martin Boland, John Karas, Vanessa Wall, Kevin Barnham, Steve Collins, Denis Scanlon
Improved locomotor function and survival of mice with increased levels of mutant superoxide dismutase 1

Journal

Journal Of Neurochemistry

Volume

130

Begin Page

44

Date

1/8/N/A

Author(s)

BR Roberts, NKH Lim, EJ McAllum, PS Donnelly, DJ Hare, PA Doble, BJ Turner, KA Price, SC Lim, BM Paterson, JL Hickey, TW Rhoads, JR Williams, KM Kanninen, LW Hung, JR Liddell, A Grubman, JF Monty, RM Llanos, DR Kramer, JFB Mercer, AI Bush, CL Masters, JA Duce, QX Li, JS Beckman, KJ Barnham, AR White, PJ Crouch
Do oxidative modifications generate neurotoxic amyloid-beta peptide?

Journal

Journal Of Neurochemistry

Volume

94

Begin Page

223

Date

1/8/N/A

Author(s)

KJ Barnham, DG Smith, GD Ciccotosto, DJ Tew, CC Curtain, CL Masters, AK Tickler, DP Smith, JD Wade, RA Cherny, AI Bush, R Cappai
Covalently linked A beta dimers

Journal

Journal Of Peptide Science

Volume

14

Begin Page

67

Date

1/8/N/A

Author(s)

Woan Mei Kok, John Karas, Denis Scanlon, Kevin J Barnham, Craig A Hutton
Reactions of Nitroplatinum Complexes. 1. 15N and 195Pt NMR Spectra of Platinum(II) Nitrite Complexes

Journal

Inorganic Chemistry

Volume

30

Begin Page

2751

Date

1/6/N/A

Author(s)

TG Appleton, KJ Barnham, JR Hall, MT Mathieson
Aspects of the Solution Chemistry of Trans-Diammineplatinum(II) Complexes

Journal

Inorganic Chemistry

Volume

31

Begin Page

3077

Date

1/1/N/A

Author(s)

TG Appleton, AJ Bailey, KJ Baraham, JR Hall
[Pt(CBDCA-O)(NH3)2(L-Methionine-S)]: Ring-Opened Adduct of the Anticancer Drug Carboplatin (“Paraplatin”). Detection of a Similar Complex in Urine by NMR Spectroscopy

Journal

Journal Of The American Chemical Society

Volume

116

Begin Page

11175

Date

1/11/N/A

Author(s)

KJ Bamham, U Frey, P del Socorro Murdoch, JD Ranford, PJ Sadler, DR Newell
Intermolecular displacement of S-bound L-methionine on platinum(II) by guanosine 5′-monophosphate: Implications for the mechanism of action of anticancer drugs

Journal

Journal Of The Chemical Society, Chemical Communications

Volume

Not Found

Begin Page

721

Date

1/12/N/A

Author(s)

KJ Barnham, MI Djuran, P Del Socorro Murdoch, PJ Sadler
[Pd(CBDCA-O,O′)(NH3)2]: The PdII analogue of a platinum anticancer drug (CBDCA=cyclobutane-1,1-dicarboxylate)

Journal

Journal Of The Chemical Society, Chemical Communications

Volume

Not Found

Begin Page

65

Date

1/12/N/A

Author(s)

KJ Barnham, MI Djuran, U Frey, MA Mazid, PJ Sadler
Platination Pathways for Reactions of Cisplatin with GG Single‐Stranded and Double‐Stranded Decanucleotides

Journal

Angewandte Chemie International Edition In English

Volume

34

Begin Page

1874

Date

15/9/N/A

Author(s)

KJ Barnham, PJ Sadler, SJ Berners Price, TA Frenkiel, U Frey
Outer-Sphere Macrochelation in [Pd(en)(5′-GMP-N7)2]-9H20 and [Pt(en)(5′-GMP-N7)2] 9H20: X-ray Crystallography and NMR Spectroscopy in Solution

Journal

Inorganic Chemistry

Volume

34

Begin Page

2826

Date

1/5/N/A

Author(s)

KJ Barnham, CJ Bauer, MI Djuran, MA Mazid, T Rau, PJ Sadler

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