Dr. Yugeesh Lankadeva is a National Heart Foundation Future Leader Research Fellow/Laboratory Head of Translational Cardiovascular and Renal Research Group, at the Florey Institute of Neuroscience and Mental Health. His research focuses on the mechanisms underlying cardiovascular failure, acute kidney injury and immunosuppression in sepsis and also the development of acute kidney injury following cardiac surgery on cardiopulmonary bypass.

Dr. Lankadeva is particularly interested in the neural and hormonal control of the circulation, from reactivity of isolated blood vessels to integrated physiological studies in the conscious whole animal. He has discovered that selective renal hypoxia occurs very early in sepsis and that this may contribute to the development of acute kidney injury. In addition, his demonstration that bladder urinary oxygen tension changes in parallel with renal medullary tissue oxygen tension, suggests that this may be used as a novel biomarker for the early detection of the development of acute kidney injury. He has also validated urinary oxygen tension as a reliable technique to accurately and continuously estimate renal medullary tissue oxygen tension during standard-of-care therapies used in intensive care units.

Dr. Lankadeva's recent discoveries has already translated into on-going clinical studies at Austin Health, Monash Health, and Royal Melbourne Hospital. Dr. Lankadeva's goal is to understand the pathological changes that occur during disease using clinically relevant large animal models, and armed with this knowledge, to develop improved therapies/interventions that can be rapidly translated to improve health outcomes for patients.

  • Location

    Florey Institute of Neuroscience and Mental Health
    30 Royal Parade
    Parkville
    3052
    Victoria
    Australia

PROJECTS SUPERVISED

Awards and achievements

Research Support:

2018-2022: National Heart Foundation Future Leader Fellowship ($ 560,000)

2016-2018: National Heart Foundation Early Career Fellowship ($ 150,000)

2018: Florey Institute Young Investigator Project Grant (sole Chief Investigator, $15,000)

2018: Florey Institute Near-Miss Project Grant (Co-Chief Investigator, $15,000)

2017: Florey Institute Project Grant (sole Chief Investigator, $ 18,000)
2017-2019: Jack Brockhoff Foundation New Investigator Medical Project Grant (sole Chief Investigator; $ 110,000)

2017-2018: University of Melbourne Early Career Researcher Project Grant (sole Chief Investigator, $ 39,648) 

Awards:

2017: John Casley-Smith Outstanding Oral Presentation Award from the Australia and New Zealand Microcirculation Society.

2017: Harold Mitchell Foundation Postdoctoral Travel Fellowship.

2016: Post-Doctoral Travel Grant from In Vitro Technologies.

2016: Young Investigator Oral Presentation Award from Florey Postdoctoral Association Symposium, Melbourne, Australia.

2016: Young Investigator Oral Presentation Prize from Fresh Science Victoria.

2015: Young Investigator Award of Excellence from the 10th World Congress for Microcirculation Conference, in recognition of an outstanding achievement by an Early Career Investigator in the field of Microcirculation, Kyoto, Japan. 

2015: Michael Perry Invited Speaker Award from the Australia and New Zealand Microcirculation Society (ANZMS) to represent ANZMS at the 10th World Congress for Microcirculation Conference, Kyoto, Japan.

2015: Best Early Career Researcher Oral Presentation Award from the Australia and New Zealand Microcirculation Society Conference, New South Wales, Australia.

2014: British Hypertension Society (BHS) Prize from the High Blood Pressure Research Council of Australia (HBPRCA) Conference to represent HBPRCA at the BHS Conference in Stratford-upon-Avon, United Kingdom.

2014: Best Early Career Investigator Oral Presentation Award from the High Blood Pressure Research Council of Australia Conference, Adelaide, Australia 

2013: Best Student Oral Presentation Award from the Australian and New Zealand Microcirculation Society Conference, Adelaide, Australia 

2012: Best Poster Award from the Australian Early Origins of Hypertension Meeting, Adelaide, Australia

2012: Young Investigator Travel Grant from the Foundation of High Blood Pressure Research Council of Australia 

2012: Post-Graduate Student Travel Award from International Society of Hypertension, Sydney, Australia 

Qualifications

National Heart Foundation Early Career Research Fellow 

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