Dr Samantha Barton

Dr Samantha Barton is an NHMRC-ARC Dementia Research Development Fellow working in the Motor Neurone Disease Laboratory at the Florey Institute of Neuroscience and Mental Health.

Dr Barton completed her PhD in 2015 at Monash University studying white matter damage in a model of preterm birth. Her keen interest in neurobiology prompted her to spend the first two years of her fellowship at the University of Edinburgh with Prof Siddharthan Chandran learning cutting-edge techniques in the handling on patient-derived induced pluripotent stem cells allowing her to delve more in-depth into the underlying pathomechanisms of white matter dysfunction.

Dr Barton's fellowship has focussed on the motor neurone diseases, more specifically amyotrophic lateral sclerosis and frontotemperal dementia, and her research goals are to understand the role of non-neuronal cells like oligodendrocytes (the major cell type of the white matter) in motor neurone disease. She uses human iPSC from patients with motor neuron disease and differentiates them into oligodendrocytes to allow phenotypic and functional analysis, comparing to iPSC-derived oligodendrocytes from otherwise healthy control patients. She also utilises mouse models and human post-mortem tissue to validate her findings.

Key collaborators

Prof Siddharthan Chandran, University of Edinburgh, UK

Prof Colin Smith, University of Edinburgh, UK

Dr Bhuvaneish Selvaraj, University of Edinburgh, UK

Dr Jenna Gregory, University of Edinburgh, UK

  • Location

    Florey Institute of Neuroscience and Mental Health
    30 Royal Parade


Awards and achievements

Fellowships and Grants

2017 Deanery of Clinical Sciences Funding Challenge Award 
2016 NHMRC-ARC Dementia Research Development Fellowship
2016 Cerebral Palsy Alliance Research Foundation Project Grant 
2015 Discovery Laboratories Educational Grant

Prizes and Awards

2018 FPA Career Development Award
2014 MIGR Postgraduate Travel Grant Award
2014 Harold Mitchell Foundation Travel Fellowship
2014 Second Prize Oral Presentation at The Ritchie Centre Colloquium
2013 PSANZ Early Research Career Travel Grant
2013 Best Poster Prize at The Ritchie Centre Colloquium
2013 Cerebral Palsy Alliance highest commended abstract
2013 Conference Education Award from National Stem Cell Foundation of Australia 
2013 Highly Commended Oral Presentation Award at Australian Society for Medical Research (ASMR) Student Symposium
2012 Cerebral Palsy Alliance highest commended abstract
2012 - 2015 Australian Postgraduate Award

Research Papers

Showing 10 of 23. VIEW ALL

Showing 10 of 23. VIEW ALL

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