Stem Cell Research
Laboratory head - Stem Cells and Neural Development Laboratory
Associate Professor Clare Parish
BBiomedSci, Ph.D
Associate Professor Clare Parish is co-head of the Florey's Basic Discovery theme.
A/Prof Clare Parish heads the Stem Cells and Neural Development. Her lab has a broad research interest relating to repairing the injured brain. Her team places a strong emphasis on understanding neural development, with the idea that recapitulating many of these early events will influence regeneration. Consequently, major research themes within her group include: understanding the neural development; directed differentiation of human pluripotent stem cells; molecular mechanisms underlying axonal plasticity and improving cell-replacement therapy for brain repair. She has a particular interest in stem cell-based therapies for the treatment of Parkinson’s disease, Stroke and Huntington’s disease.
Clare obtained her PhD (Monash) in 2002, followed by 5years postdoctoral research at the Karolinska Institute (Stockholm, Sweden). She returned to Australia in 2007, establishing an independent research group in 2009. She has been the recipient of numerous fellowships inclusive of NHMRC CJ Martin Fellowship, Human Frontiers Fellowship, NHMRC Career Development Fellowship, Viertel Senior Medical Fellowship and currently holds an NHMRC Senior Research Fellowship. Clare has received ongoing NHMRC, ARC and pilantrophic funding throughout her independent career, has >85 career publications, and is an editor for a number of journals including the British Journal of Pharmacology and Cell Death & Disease.
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Location
Florey Institute of Neuroscience and Mental Health
30 Royal Parade
Parkville
3052
Victoria
Australia
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Research teams
Awards and achievements
Viertal Foundation Senior Medical Research Fellowship, 2011
Qualifications
Ph.D (University of Melbourne)
Research Papers
Showing 10 of 95. VIEW ALL
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Generation of four iPSC lines from peripheral blood mononuclear cells (PBMCs) of an attention deficit hyperactivity disorder (ADHD) individual and a healthy sibling in an Australia-Caucasian familyAuthor(s): Tong, J., Lee, K.M., Liu, X., Nefzger, C.M., Vijayakumar, P., Hawi, Z., Pang, K.C., Parish, C.L., Polo, J.M., Bellgrove, M.A.
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Axonal Growth of Midbrain Dopamine Neurons is Modulated by the Cell Adhesion Molecule ALCAM Through Trans-Heterophilic Interactions with L1cam, Chl1, and SemaphorinsThe Journal of neuroscience : the official journal of the Society for Neuroscience
- Volume: 39
- Page(s): 6656-6667
- Year: 2019
Author(s): Bye, C.R., Rytova, V., Alsanie, W.F., Parish, C.L., Thompson, L.H.Author(s): Bye, C.R., Rytova, V., Alsanie, W.F., Parish, C.L., Thompson, L.H. -
Harnessing stem cells and biomaterials to promote neural repairBritish Journal of Pharmacology
- Volume: 176
- Page(s): 355-368
- Year: 2019
Author(s): Bruggeman, K.F., Moriarty, N., Dowd, E., Nisbet, D.R., Parish, C.L.Author(s): Bruggeman, K.F., Moriarty, N., Dowd, E., Nisbet, D.R., Parish, C.L. -
Isolation of LMX1a Ventral Midbrain Progenitors Improves the Safety and Predictability of Human Pluripotent Stem Cell-Derived Neural Transplants in Parkinsonian DiseaseThe Journal of neuroscience : the official journal of the Society for Neuroscience
- Volume: 39
- Page(s): 9521-9531
- Year: 2019
Author(s): de Luzy, I.R., Niclis, J.C., Gantner, C.W., Kauhausen, J.A., Hunt, C.P.J., Ermine, C., Pouton, C.W., Thompson, L.H., Parish, C.L.Author(s): de Luzy, I.R., Niclis, J.C., Gantner, C.W., Kauhausen, J.A., Hunt, C.P.J., Ermine, C., Pouton, C.W., Thompson, L.H., Parish, C.L. -
Primary tissue for cellular brain repair in Parkinson's disease: Promise, problems and the potential of biomaterialsEuropean Journal of Neuroscience
- Year: 2019
Author(s): Moriarty, N., Parish, C.L., Dowd, E.Author(s): Moriarty, N., Parish, C.L., Dowd, E. -
Inhibition of amyloid beta toxicity in zebrafish with a chaperone-gold nanoparticle dual strategyNature Communications
- Volume: 10
- Year: 2019
Author(s): Javed, I., Peng, G., Xing, Y., Yu, T., Zhao, M., Kakinen, A., Faridi, A., Parish, C.L., Ding, F., Davis, T.P., Ke, P.C., Lin, S.Author(s): Javed, I., Peng, G., Xing, Y., Yu, T., Zhao, M., Kakinen, A., Faridi, A., Parish, C.L., Ding, F., Davis, T.P., Ke, P.C., Lin, S. -
Transcriptional Profiling of Xenogeneic Transplants: Examining Human Pluripotent Stem Cell-Derived Grafts in the Rodent BrainStem Cell Reports
- Volume: 13
- Page(s): 877-890
- Year: 2019
Author(s): Bye, C.R., Penna, V., de Luzy, I.R., Gantner, C.W., Hunt, C.P.J., Thompson, L.H., Parish, C.L.Author(s): Bye, C.R., Penna, V., de Luzy, I.R., Gantner, C.W., Hunt, C.P.J., Thompson, L.H., Parish, C.L. -
Viral Delivery of GDNF Promotes Functional Integration of Human Stem Cell Grafts in Parkinson's Disease.Cell stem cell
- Year: 13/02/2020
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The application of human pluripotent stem cells to model the neuronal and glial components of neurodevelopmental disorders.Molecular psychiatry
- Year: 27/08/2019
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Biomimetic Materials and Their Utility in Modeling the 3-Dimensional Neural Environment.iScience
- Year: 19/12/2019
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Using minimalist self-assembling peptides as hierarchical scaffolds to stabilise growth factors and promote stem cell integration in the injured brainJournal of Tissue Engineering and Regenerative Medicine
- Volume: 12
- Page(s): e1571-e1579
- Year: 2018
Author(s): Rodriguez, A.L., Bruggeman, K.F., Wang, Y., Wang, T.Y., Williams, R.J., Parish, C.L., Nisbet, D.R.Author(s): Rodriguez, A.L., Bruggeman, K.F., Wang, Y., Wang, T.Y., Williams, R.J., Parish, C.L., Nisbet, D.R. -
Modelling the dopamine and noradrenergic cell loss that occurs in Parkinson's disease and the impact on hippocampal neurogenesisHippocampus
- Year: 2018
Author(s): Ermine, C.M., Wright, J.L., Frausin, S., Kauhausen, J.A., Parish, C.L., Stanic, D., Thompson, L.H.Author(s): Ermine, C.M., Wright, J.L., Frausin, S., Kauhausen, J.A., Parish, C.L., Stanic, D., Thompson, L.H. -
A PITX3-EGFP Reporter Line Reveals Connectivity of Dopamine and Non-dopamine Neuronal Subtypes in Grafts Generated from Human Embryonic Stem CellsStem Cell Reports
- Volume: 9
- Page(s): 868-882
- Year: 2017
Author(s): Niclis, J.C., Gantner, C.W., Hunt, C.P.J., Kauhausen, J.A., Durnall, J.C., Haynes, J.M., Pouton, C.W., Parish, C.L., Thompson, L.H.Author(s): Niclis, J.C., Gantner, C.W., Hunt, C.P.J., Kauhausen, J.A., Durnall, J.C., Haynes, J.M., Pouton, C.W., Parish, C.L., Thompson, L.H. -
Efficiently specified ventral midbrain dopamine neurons from human pluripotent stem cells under Xeno-free conditions restore motor deficits in Parkinsonian rodentsStem Cells Translational Medicine
- Volume: 6
- Page(s): 937-948
- Year: 2017
Author(s): Niclis, J.C., Gantner, C.W., Alsanie, W.F., McDougall, S.J., Bye, C.R., Elefanty, A.G., Stanley, E.G., Haynes, J.M., Pouton, C.W., Thompson, L.H., Parish, C.L.Author(s): Niclis, J.C., Gantner, C.W., Alsanie, W.F., McDougall, S.J., Bye, C.R., Elefanty, A.G., Stanley, E.G., Haynes, J.M., Pouton, C.W., Thompson, L.H., Parish, C.L. -
Generation of four iPSC lines from peripheral blood mononuclear cells (PBMCs) of an Attention Deficit Hyperactivity Disorder (ADHD) individual and a healthy sibling in an Australia-Caucasian familyStem Cell Research
- Year: 27/11/2018
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Local Injection of Endothelin-1 in the Early Neonatal Rat Brain Models Ischemic Damage Associated with Motor Impairment and Diffuse Loss in Brain VolumeNeuroscience
- Year: 21/11/2018
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Specification of murine ground state pluripotent stem cells to regional neuronal populations.Scientific Reports
- Year: 22/11/2018
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Shear containment of BDNF within molecular hydrogels promote human stem cell engraftment and post-infarction remodeling in stroke.Advanced Biosystems
- Year: 07/2018
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Local Injection of Endothelin-1 in the Early Neonatal Rat Brain Models Ischemic Damage Associated with Motor Impairment and Diffuse Loss in Brain VolumeNeuroscience
- Volume: 393
- Page(s): 110-122
- Year: 2018
Author(s): Wright, J.L., Chu, H.X., Kagan, B.J., Ermine, C.M., Kauhausen, J.A., Parish, C.L., Sobey, C.G., Thompson, L.H.Author(s): Wright, J.L., Chu, H.X., Kagan, B.J., Ermine, C.M., Kauhausen, J.A., Parish, C.L., Sobey, C.G., Thompson, L.H. -
Shear Containment of BDNF within Molecular Hydrogels Promotes Human Stem Cell Engraftment and Postinfarction Remodeling in StrokeAdvanced Biosystems
- Volume: 2
- Page(s): 1800113
- Year: 09/2018
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Dopamine Receptor Antagonists Enhance Proliferation and Neurogenesis of Midbrain Lmx1a-expressing ProgenitorsScientific Reports
- Volume: 6
- Year: 2016
Author(s): Hedlund, E., Belnoue, L., Theofilopoulos, S., Salto, C., Bye, C., Parish, C., Deng, Q., Kadkhodaei, B., Ericson, J., Arenas, E., Perlmann, T., Simon, A.Author(s): Hedlund, E., Belnoue, L., Theofilopoulos, S., Salto, C., Bye, C., Parish, C., Deng, Q., Kadkhodaei, B., Ericson, J., Arenas, E., Perlmann, T., Simon, A. -
GAPTrap: A Simple Expression System for Pluripotent Stem Cells and Their DerivativesStem Cell Reports
- Volume: 7
- Page(s): 518-526
- Year: 2016
Author(s): Kao, T., Labonne, T., Niclis, J.C., Chaurasia, R., Lokmic, Z., Qian, E., Bruveris, F.F., Howden, S.E., Motazedian, A., Schiesser, J.V., Costa, M., Sourris, K., Ng, E., Anderson, D., Giudice, A., Farlie, P., Cheung, M., Lamande, S.R., Penington, A.J., Parish, C.L., Thomson, L.H., Rafii, A., Elliott, D.A., Elefanty, A.G., Stanley, E.G.Author(s): Kao, T., Labonne, T., Niclis, J.C., Chaurasia, R., Lokmic, Z., Qian, E., Bruveris, F.F., Howden, S.E., Motazedian, A., Schiesser, J.V., Costa, M., Sourris, K., Ng, E., Anderson, D., Giudice, A., Farlie, P., Cheung, M., Lamande, S.R., Penington, A.J., Parish, C.L., Thomson, L.H., Rafii, A., Elliott, D.A., Elefanty, A.G., Stanley, E.G. -
Long-distance axonal growth and protracted functional maturation of neurons derived from human induced pluripotent stem cells after intracerebral transplantationStem Cells Translational Medicine
- Volume: 6
- Page(s): 1547-1556
- Year: 2017
Author(s): Niclis, J.C., Turner, C., Durnall, J., McDougal, S., Kauhausen, J.A., Leaw, B., Dottori, M., Parish, C.L., Thompson, L.H.Author(s): Niclis, J.C., Turner, C., Durnall, J., McDougal, S., Kauhausen, J.A., Leaw, B., Dottori, M., Parish, C.L., Thompson, L.H. -
Homophilic binding of the neural cell adhesion molecule CHL1 regulates development of ventral midbrain dopaminergic pathwaysScientific Reports
- Volume: 7
- Year: 2017
Author(s): Alsanie, W.F., Penna, V., Schachner, M., Thompson, L.H., Parish, C.L.Author(s): Alsanie, W.F., Penna, V., Schachner, M., Thompson, L.H., Parish, C.L. -
Huntingtin Inclusions Trigger Cellular Quiescence, Deactivate Apoptosis, and Lead to Delayed NecrosisCell Reports
- Volume: 19
- Page(s): 919-927
- Year: 2017
Author(s): Ramdzan, Y.M., Trubetskov, M.M., Ormsby, A.R., Newcombe, E.A., Sui, X., Tobin, M.J., Bongiovanni, M.N., Gras, S.L., Dewson, G., Miller, J.M.L., Finkbeiner, S., Moily, N.S., Niclis, J., Parish, C.L., Purcell, A.W., Baker, M.J., Wilce, J.A., Waris, S., Stojanovski, D., Böcking, T., Ang, C.-S., Ascher, D.B., Reid, G.E., Hatters, D.M.Author(s): Ramdzan, Y.M., Trubetskov, M.M., Ormsby, A.R., Newcombe, E.A., Sui, X., Tobin, M.J., Bongiovanni, M.N., Gras, S.L., Dewson, G., Miller, J.M.L., Finkbeiner, S., Moily, N.S., Niclis, J., Parish, C.L., Purcell, A.W., Baker, M.J., Wilce, J.A., Waris, S., Stojanovski, D., Böcking, T., Ang, C.-S., Ascher, D.B., Reid, G.E., Hatters, D.M. -
Combined immunohistochemical and retrograde tracing reveals little evidence of innervation of the rat dentate gyrus by midbrain dopamine neuronsFrontiers in Biology
- Volume: 11
- Page(s): 246-255
- Year: 2016
Author(s): Ermine, C.M., Wright, J.L., Parish, C.L., Stanic, D., Thompson, L.H.Author(s): Ermine, C.M., Wright, J.L., Parish, C.L., Stanic, D., Thompson, L.H. -
Functionalized composite scaffolds improve the engraftment of transplanted dopaminergic progenitors in a mouse model of Parkinson's diseaseBiomaterials
- Volume: 74
- Page(s): 89-98
- Year: 2016
Author(s): Wang, T.-Y., Bruggeman, K.F., Kauhausen, J.A., Rodriguez, A.L., Nisbet, D.R., Parish, C.L.Author(s): Wang, T.-Y., Bruggeman, K.F., Kauhausen, J.A., Rodriguez, A.L., Nisbet, D.R., Parish, C.L. -
Temporally controlled growth factor delivery from a self-assembling peptide hydrogel and electrospun nanofibre composite scaffoldNanoscale
- Volume: 9
- Page(s): 13661-13669
- Year: 2017
Author(s): Bruggeman, K.F., Wang, Y., Maclean, F.L., Parish, C.L., Williams, R.J., Nisbet, D.R.Author(s): Bruggeman, K.F., Wang, Y., Maclean, F.L., Parish, C.L., Williams, R.J., Nisbet, D.R. -
Peptide-Based Scaffolds Support Human Cortical Progenitor Graft Integration to Reduce Atrophy and Promote Functional Repair in a Model of StrokeCell Reports
- Volume: 20
- Page(s): 1964-1977
- Year: 2017
Author(s): Somaa, F.A., Wang, T.-Y., Niclis, J.C., Bruggeman, K.F., Kauhausen, J.A., Guo, H., McDougall, S., Williams, R.J., Nisbet, D.R., Thompson, L.H., Parish, C.L.Author(s): Somaa, F.A., Wang, T.-Y., Niclis, J.C., Bruggeman, K.F., Kauhausen, J.A., Guo, H., McDougall, S., Williams, R.J., Nisbet, D.R., Thompson, L.H., Parish, C.L. -
Specification of murine ground state pluripotent stem cells to regional neuronal populationsScientific Reports
- Volume: 7
- Year: 2017
Author(s): Alsanie, W.F., Niclis, J.C., Hunt, C.P., De Luzy, I.R., Penna, V., Bye, C.R., Pouton, C.W., Haynes, J., Firas, J., Thompson, L.H., Parish, C.L.Author(s): Alsanie, W.F., Niclis, J.C., Hunt, C.P., De Luzy, I.R., Penna, V., Bye, C.R., Pouton, C.W., Haynes, J., Firas, J., Thompson, L.H., Parish, C.L. -
Integrating Biomaterials and Stem Cells for Neural RegenerationStem Cells and Development
- Volume: 25
- Page(s): 214-226
- Year: 2016
Author(s): Maclean, F.L., Rodriguez, A.L., Parish, C.L., Williams, R.J., Nisbet, D.R.Author(s): Maclean, F.L., Rodriguez, A.L., Parish, C.L., Williams, R.J., Nisbet, D.R. -
Genome-wide binding and mechanistic analyses of Smchd1-mediated epigenetic regulationProceedings of the National Academy of Sciences of the United States of America
- Volume: 112
- Page(s): E3535-E3544
- Year: 2015
Author(s): Chen, K., Hu, J., Moore, D.L., Liu, R., Kessans, S.A., Breslin, K., Lucet, I.S., Keniry, A., Leong, H.S., Parish, C.L., Hilton, D.J., Lemmers, R.J.L.F., Van Der Maarel, S.M., Czabotar, P.E., Dobson, R.C.J., Ritchie, M.E., Kay, G.F., Murphy, J.M., Blewitt, M.E.Author(s): Chen, K., Hu, J., Moore, D.L., Liu, R., Kessans, S.A., Breslin, K., Lucet, I.S., Keniry, A., Leong, H.S., Parish, C.L., Hilton, D.J., Lemmers, R.J.L.F., Van Der Maarel, S.M., Czabotar, P.E., Dobson, R.C.J., Ritchie, M.E., Kay, G.F., Murphy, J.M., Blewitt, M.E. -
14-3-3ζ deficient mice in the BALB/c background display behavioural and anatomical defects associated with neurodevelopmental disordersScientific Reports
- Volume: 5
- Year: 2015
Author(s): Xu, X., Jaehne, E.J., Greenberg, Z., McCarthy, P., Saleh, E., Parish, C.L., Camera, D., Heng, J., Haas, M., Baune, B.T., Ratnayake, U., Van Den Buuse, M., Lopez, A.F., Ramshaw, H.S., Schwarz, Q.Author(s): Xu, X., Jaehne, E.J., Greenberg, Z., McCarthy, P., Saleh, E., Parish, C.L., Camera, D., Heng, J., Haas, M., Baune, B.T., Ratnayake, U., Van Den Buuse, M., Lopez, A.F., Ramshaw, H.S., Schwarz, Q. -
Meningeal cells influence midbrain development and the engraftment of dopamine progenitors in parkinsonian miceExperimental Neurology
- Volume: 267
- Page(s): 30-41
- Year: 2015
Author(s): Somaa, F.A., Bye, C.R., Thompson, L.H., Parish, C.L.Author(s): Somaa, F.A., Bye, C.R., Thompson, L.H., Parish, C.L. -
Chondroitinase improves midbrain pathway reconstruction by transplanted dopamine progenitors in Parkinsonian miceMolecular and Cellular Neuroscience
- Volume: 69
- Page(s): 22-29
- Year: 2015
Author(s): Kauhausen, J.A., Thompson, L.H., Parish, C.L.Author(s): Kauhausen, J.A., Thompson, L.H., Parish, C.L. -
Tailoring minimalist self-assembling peptides for localized viral vector gene deliveryNano Research
- Volume: 9
- Page(s): 674-684
- Year: 2016
Author(s): Rodriguez, A.L., Wang, T.-Y., Bruggeman, K.F., Li, R., Williams, R.J., Parish, C.L., Nisbet, D.R.Author(s): Rodriguez, A.L., Wang, T.-Y., Bruggeman, K.F., Li, R., Williams, R.J., Parish, C.L., Nisbet, D.R. -
Over-expression of meteorin drives gliogenesis following striatal injuryFrontiers in Cellular Neuroscience
- Volume: 10
- Year: 2016
Author(s): Wright, J.L., Ermine, C.M., Jørgensen, J.R., Parish, C.L., Thompson, L.H.Author(s): Wright, J.L., Ermine, C.M., Jørgensen, J.R., Parish, C.L., Thompson, L.H. -
Characterisation of the stability and bio-functionality of tethered proteins on bioengineered scaffolds: Implications for stem cell biology and tissue repairIFMBE Proceedings
- Volume: 47
- Page(s): 46-49
- Year: 2015
Author(s): Wang, T.-Y., Bruggeman, K.A.F., Sheean, R.K., Nisbet, D.R., Parish, C.L.Author(s): Wang, T.-Y., Bruggeman, K.A.F., Sheean, R.K., Nisbet, D.R., Parish, C.L. -
Temporally controlled release of multiple growth factors from a self-assembling peptide hydrogelNanotechnology
- Volume: 27
- Year: 2016
Author(s): Bruggeman, K.F., Rodriguez, A.L., Parish, C.L., Williams, R.J., Nisbet, D.R.Author(s): Bruggeman, K.F., Rodriguez, A.L., Parish, C.L., Williams, R.J., Nisbet, D.R. -
Motor and behavioral phenotype in conditional mutants with targeted ablation of cortical D1 dopamine receptor-expressing cellsNeurobiology of Disease
- Volume: 76
- Page(s): 137-158
- Year: 2015
Author(s): Jiang, L., O'Leary, C., Kim, H.A., Parish, C.L., Massalas, J., Waddington, J.L., Ehrlich, M.E., Schütz, G., Gantois, I., Lawrence, A.J., Drago, J.Author(s): Jiang, L., O'Leary, C., Kim, H.A., Parish, C.L., Massalas, J., Waddington, J.L., Ehrlich, M.E., Schütz, G., Gantois, I., Lawrence, A.J., Drago, J. -
Modulating Wnt signaling to improve cell replacement therapy for Parkinson's diseaseJournal of Molecular Cell Biology
- Volume: 6
- Page(s): 54-63
- Year: 2014
Author(s): Parish, C.L., Thompson, L.H.Author(s): Parish, C.L., Thompson, L.H. -
Functional characterization of Friedreich ataxia iPS-derived neuronal progenitors and their integration in the adult brainPLoS ONE
- Volume: 9
- Year: 2014
Author(s): Bird, M.J., Needham, K., Frazier, A.E., Rooijen, J., Leung, J., Hough, S., Denham, M., Thornton, M.E., Parish, C.L., Nayagam, B.A., Pera, M., Thorburn, D.R., Thompson, L.H., Dottori, M.Author(s): Bird, M.J., Needham, K., Frazier, A.E., Rooijen, J., Leung, J., Hough, S., Denham, M., Thornton, M.E., Parish, C.L., Nayagam, B.A., Pera, M., Thorburn, D.R., Thompson, L.H., Dottori, M. -
3D Electrospun scaffolds promote a cytotrophic phenotype of cultured primary astrocytesJournal of Neurochemistry
- Volume: 130
- Page(s): 215-226
- Year: 2014
Author(s): Lau, C.L., Kovacevic, M., Tingleff, T.S., Forsythe, J.S., Cate, H.S., Merlo, D., Cederfur, C., Maclean, F.L., Parish, C.L., Horne, M.K., Nisbet, D.R., Beart, P.M.Author(s): Lau, C.L., Kovacevic, M., Tingleff, T.S., Forsythe, J.S., Cate, H.S., Merlo, D., Cederfur, C., Maclean, F.L., Parish, C.L., Horne, M.K., Nisbet, D.R., Beart, P.M. -
Diverse roles for Wnt7a in ventral midbrain neurogenesis and dopaminergic axon morphogenesisStem Cells and Development
- Volume: 23
- Page(s): 1991-2003
- Year: 2014
Author(s): Fernando, C.V., Kele, J., Bye, C.R., Niclis, J.C., Alsanie, W., Blakely, B.D., Stenman, J., Turner, B.J., Parish, C.L.Author(s): Fernando, C.V., Kele, J., Bye, C.R., Niclis, J.C., Alsanie, W., Blakely, B.D., Stenman, J., Turner, B.J., Parish, C.L. -
Transcriptome analysis reveals transmembrane targets on transplantable midbrain dopamine progenitorsProceedings of the National Academy of Sciences of the United States of America
- Volume: 112
- Page(s): E1946-E1955
- Year: 2015
Author(s): Bye, C.R., Jönsson, M.E., Björklund, A., Parish, C.L., Thompson, L.H.Author(s): Bye, C.R., Jönsson, M.E., Björklund, A., Parish, C.L., Thompson, L.H. -
Characterization of the stability and bio-functionality of tethered proteins on bioengineered scaffolds: Implications for stem cell biology and tissue repairJournal of Biological Chemistry
- Volume: 289
- Page(s): 15044-15051
- Year: 2014
Author(s): Wang, T.-Y., Bruggeman, K.A.F., Sheean, R.K., Turner, B.J., Nisbet, D.R., Parish, C.L.Author(s): Wang, T.-Y., Bruggeman, K.A.F., Sheean, R.K., Turner, B.J., Nisbet, D.R., Parish, C.L. -
In vivo assessment of grafted cortical neural progenitor cells and host response to functionalized self-assembling peptide hydrogels and the implications for tissue repairJournal of Materials Chemistry B
- Volume: 2
- Page(s): 7771-7778
- Year: 2014
Author(s): Rodriguez, A.L., Wang, T.Y., Bruggeman, K.F., Horgan, C.C., Li, R., Williams, R.J., Parish, C.L., Nisbet, D.R.Author(s): Rodriguez, A.L., Wang, T.Y., Bruggeman, K.F., Horgan, C.C., Li, R., Williams, R.J., Parish, C.L., Nisbet, D.R. -
Resolving pathobiological mechanisms relating to Huntington disease: Gait, balance, and involuntary movements in mice with targeted ablation of striatal D1 dopamine receptor cellsNeurobiology of Disease
- Volume: 62
- Page(s): 323-337
- Year: 2014
Author(s): Kim, H.A., Jiang, L., Madsen, H., Parish, C.L., Massalas, J., Smardencas, A., O'Leary, C., Gantois, I., O'Tuathaigh, C., Waddington, J.L., Ehrlich, M.E., Lawrence, A.J., Drago, J.Author(s): Kim, H.A., Jiang, L., Madsen, H., Parish, C.L., Massalas, J., Smardencas, A., O'Leary, C., Gantois, I., O'Tuathaigh, C., Waddington, J.L., Ehrlich, M.E., Lawrence, A.J., Drago, J. -
A Fully Human Inhibitory Monoclonal Antibody to the Wnt Receptor RYKPLoS ONE
- Volume: 8
- Year: 2013
Author(s): Halford, M.M., Macheda, M.L., Parish, C.L., Takano, E.A., Fox, S., Layton, D., Nice, E., Stacker, S.A.Author(s): Halford, M.M., Macheda, M.L., Parish, C.L., Takano, E.A., Fox, S., Layton, D., Nice, E., Stacker, S.A. -
In vivo assessment of grafted cortical neural progenitor cells and host response to functionalized self-assembling peptide hydrogels and implications for tissue repairJournal of Materials Chemistry B
- Year: 2014
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Locomotor hyperactivity in 14-3-3ζ KO mice is associated with dopamine transporter dysfunctionTranslational Psychiatry
- Volume: 3
- Year: 2013
Author(s): Ramshaw, H., Xu, X., Jaehne, E.J., McCarthy, P., Greenberg, Z., Saleh, E., McClure, B., Woodcock, J., Kabbara, S., Wiszniak, S., Wang, T.-Y., Parish, C., Van Den Buuse, M., Baune, B.T., Lopez, A., Schwarz, Q.Author(s): Ramshaw, H., Xu, X., Jaehne, E.J., McCarthy, P., Greenberg, Z., Saleh, E., McClure, B., Woodcock, J., Kabbara, S., Wiszniak, S., Wang, T.-Y., Parish, C., Van Den Buuse, M., Baune, B.T., Lopez, A., Schwarz, Q. -
Ryk, a receptor regulating wnt5a-mediated neurogenesis and axon morphogenesis of ventral midbrain dopaminergic neuronsStem Cells and Development
- Volume: 22
- Page(s): 2132-2144
- Year: 2013
Author(s): Blakely, B.D., Bye, C.R., Fernando, C.V., Prasad, A.A., Jeroen Pasterkamp, R., MacHeda, M.L., Stacker, S.A., Parish, C.L.Author(s): Blakely, B.D., Bye, C.R., Fernando, C.V., Prasad, A.A., Jeroen Pasterkamp, R., MacHeda, M.L., Stacker, S.A., Parish, C.L. -
Biofunctionalisation of polymeric scaffolds for neural tissue engineeringJournal of Biomaterials Applications
- Volume: 27
- Page(s): 369-390
- Year: 2012
Author(s): Wang, T.Y., Forsythe, J.S., Parish, C.L., Nisbet, D.R.Author(s): Wang, T.Y., Forsythe, J.S., Parish, C.L., Nisbet, D.R. -
Developing stem cell-based therapies for neural repairFrontiers in Cellular Neuroscience
- Volume: 7
- Year: 2013
Author(s): Parish, C.L., Thompson, L.H.Author(s): Parish, C.L., Thompson, L.H. -
Efficient expansion and dopaminergic differentiation of human fetal ventral midbrain neural stem cells by midbrain morphogensNeurobiology of Disease
- Volume: 49
- Page(s): 118-127
- Year: 2013
Author(s): Ribeiro, D., Laguna Goya, R., Ravindran, G., Vuono, R., Parish, C.L., Foldi, C., Piroth, T., Yang, S., Parmar, M., Nikkhah, G., Hjerling-Leffler, J., Lindvall, O., Barker, R.A., Arenas, E.Author(s): Ribeiro, D., Laguna Goya, R., Ravindran, G., Vuono, R., Parish, C.L., Foldi, C., Piroth, T., Yang, S., Parmar, M., Nikkhah, G., Hjerling-Leffler, J., Lindvall, O., Barker, R.A., Arenas, E. -
Transplantation of fetal midbrain dopamine progenitors into a rodent model of Parkinson's diseaseMethods in Molecular Biology
- Volume: 1059
- Page(s): 169-180
- Year: 2013
Author(s): Thompson, L.H., Parish, C.L.Author(s): Thompson, L.H., Parish, C.L. -
Birth dating of midbrain dopamine neurons identifies A9 enriched tissue for transplantation into Parkinsonian miceExperimental Neurology
- Volume: 236
- Page(s): 58-68
- Year: 2012
Author(s): Bye, C.R., Thompson, L.H., Parish, C.L.Author(s): Bye, C.R., Thompson, L.H., Parish, C.L. -
Cell intrinsic and extrinsic factors contribute to enhance neural circuit reconstruction following transplantation in Parkinsonian miceJournal of Physiology
- Volume: 591
- Page(s): 77-91
- Year: 2013
Author(s): Kauhausen, J., Thompson, L.H., Parish, C.L.Author(s): Kauhausen, J., Thompson, L.H., Parish, C.L. -
Neurons derived from human embryonic stem cells extend long-distance axonal projections through growth along host white matter tracts after intra-cerebral transplantationFrontiers in Cellular Neuroscience
- Year: 2012
Author(s): Denham, M., Parish, C.L., Leaw, B., Wright, J., Reid, C.A., Petrou, S., Dottori, M., Thompson, L.H.Author(s): Denham, M., Parish, C.L., Leaw, B., Wright, J., Reid, C.A., Petrou, S., Dottori, M., Thompson, L.H. -
Tuning the amino acid sequence of minimalist peptides to present biological signals via charge neutralised self assemblySoft Matter
- Volume: 9
- Page(s): 3915-3919
- Year: 2013
Author(s): Rodriguez, A.L., Parish, C.L., Nisbet, D.R., Williams, R.J.Author(s): Rodriguez, A.L., Parish, C.L., Nisbet, D.R., Williams, R.J. -
The potential of stem cells and tissue engineered scaffolds for repair of the central nervous systemStem Cells and Cancer Stem Cells, Volume 4: Therapeutic Applications in Disease and Injury
- Page(s): 97-111
- Year: 2012
Author(s): Rodriguez, A.L., Nisbet, D.R., Parish, C.L.Author(s): Rodriguez, A.L., Nisbet, D.R., Parish, C.L. -
The human testis-determining factor SRY localizes in midbrain dopamine neurons and regulates multiple components of catecholamine synthesis and metabolismJournal of Neurochemistry
- Volume: 122
- Page(s): 260-271
- Year: 2012
Author(s): Czech, D.P., Lee, J., Sim, H., Parish, C.L., Vilain, E., Harley, V.R.Author(s): Czech, D.P., Lee, J., Sim, H., Parish, C.L., Vilain, E., Harley, V.R. -
Neuronal activity regulates expression of tyrosine hydroxylase in adult mouse substantia nigra pars compacta neuronsJournal of Neurochemistry
- Volume: 116
- Page(s): 646-658
- Year: 2011
Author(s): Aumann, T.D., Egan, K., Lim, J., Boon, W.C., Bye, C.R., Chua, H.K., Baban, N., Parish, C.L., Bobrovskaya, L., Dickson, P., Horne, M.K.Author(s): Aumann, T.D., Egan, K., Lim, J., Boon, W.C., Bye, C.R., Chua, H.K., Baban, N., Parish, C.L., Bobrovskaya, L., Dickson, P., Horne, M.K. -
SFRP1 and SFRP2 dose-dependently regulate midbrain dopamine neuron development in vivo and in embryonic stem cellsStem Cells
- Volume: 30
- Page(s): 865-875
- Year: 2012
Author(s): Kele, J., Andersson, E.R., Villaescusa, J.C., Cajanek, L., Parish, C.L., Bonilla, S., Toledo, E.M., Bryja, V., Rubin, J.S., Shimono, A., Arenas, E.Author(s): Kele, J., Andersson, E.R., Villaescusa, J.C., Cajanek, L., Parish, C.L., Bonilla, S., Toledo, E.M., Bryja, V., Rubin, J.S., Shimono, A., Arenas, E. -
Promoting engraftment of transplanted neural stem cells/progenitors using biofunctionalised electrospun scaffoldsBiomaterials
- Volume: 33
- Page(s): 9188-9197
- Year: 2012
Author(s): Wang, T.-Y., Forsythe, J.S., Nisbet, D.R., Parish, C.L.Author(s): Wang, T.-Y., Forsythe, J.S., Nisbet, D.R., Parish, C.L. -
Chronic cocaine administration reduces striatal dopamine terminal density and striatal dopamine release which leads to drug-seeking behaviourNeuroscience
- Volume: 174
- Page(s): 143-150
- Year: 2011
Author(s): Lee, J., Parish, C.L., Tomas, D., Horne, M.K.Author(s): Lee, J., Parish, C.L., Tomas, D., Horne, M.K. -
Functional integration of grafted neural stem cell-derived dopaminergic neurons monitored by optogenetics in an in vitro Parkinson modelPLoS ONE
- Volume: 6
- Year: 2011
Author(s): Tønnesen, J., Parish, C.L., Sørensen, A.T., Andersson, A., Lundberg, C., Deisseroth, K., Arenas, E., Lindvall, O., Kokaia, M.Author(s): Tønnesen, J., Parish, C.L., Sørensen, A.T., Andersson, A., Lundberg, C., Deisseroth, K., Arenas, E., Lindvall, O., Kokaia, M. -
Development of an in vitro model to evaluate the regenerative capacity of adult brain-derived tyrosine hydroxylase-expressing dopaminergic neuronsNeurochemical Research
- Volume: 36
- Page(s): 967-977
- Year: 2011
Author(s): Majd, S., Smardencas, A., Parish, C.L., Drago, J.Author(s): Majd, S., Smardencas, A., Parish, C.L., Drago, J. -
Wnt5a regulates midbrain dopaminergic axon growth and guidancePLoS ONE
- Volume: 6
- Year: 2011
Author(s): Blakely, B.D., Bye, C.R., Fernando, C.V., Horne, M.K., Macheda, M.L., Stacker, S.A., Arenas, E., Parish, C.L.Author(s): Blakely, B.D., Bye, C.R., Fernando, C.V., Horne, M.K., Macheda, M.L., Stacker, S.A., Arenas, E., Parish, C.L. -
Cellular up-regulation of Nedd4 family interacting protein 1 (Ndfip1) using low levels of bioactive cobalt complexesJournal of Biological Chemistry
- Volume: 286
- Page(s): 8555-8564
- Year: 2011
Author(s): Schieber, C., Howitt, J., Putz, U., White, J.M., Parish, C.L., Donnelly, P.S., Tan, S.-S.Author(s): Schieber, C., Howitt, J., Putz, U., White, J.M., Parish, C.L., Donnelly, P.S., Tan, S.-S. -
Wnt/β-catenin signaling blockade promotes neuronal induction and dopaminergic differentiation in embryonic stem cellsStem Cells
- Volume: 27
- Page(s): 2917-2927
- Year: 2009
Author(s): Čajánek, L., Ribeiro, D., Liste, I., Parish, C.L., Bryja, V., Arenas, E.Author(s): Čajánek, L., Ribeiro, D., Liste, I., Parish, C.L., Bryja, V., Arenas, E. -
A small synthetic cripto blocking peptide improves neural induction, dopaminergic differentiation, and functional integration of mouse embryonic stem cells in a rat model of Parkinson's diseaseStem Cells
- Volume: 28
- Page(s): 1326-1337
- Year: 2010
Author(s): Lonardo, E., Parish, C.L., Ponticelli, S., Marasco, D., Ribeiro, D., Ruvo, M., De Falco, S., Arenas, E., Minchiotti, G.Author(s): Lonardo, E., Parish, C.L., Ponticelli, S., Marasco, D., Ribeiro, D., Ruvo, M., De Falco, S., Arenas, E., Minchiotti, G. -
Creating a ventral midbrain stem cell niche in an animal model for parkinson's diseaseStem Cells and Development
- Volume: 19
- Page(s): 1995-2007
- Year: 2010
Author(s): Fernando, C.V., Moses, D., Parish, C.L., Tomas, D., Drago, J., Horne, M.K.Author(s): Fernando, C.V., Moses, D., Parish, C.L., Tomas, D., Drago, J., Horne, M.K. -
Three-dimensional nanofibrous scaffolds incorporating immobilized bdnf promote proliferation and differentiation of cortical neural stem cellsStem Cells and Development
- Volume: 19
- Page(s): 843-852
- Year: 2010
Author(s): Horne, M.K., Nisbet, D.R., Forsythe, J.S., Parish, C.L.Author(s): Horne, M.K., Nisbet, D.R., Forsythe, J.S., Parish, C.L. -
Inhibition of JNK increases survival of transplanted dopamine neurons in Parkinsonian rats [2]Cell Death and Differentiation
- Volume: 14
- Page(s): 381-383
- Year: 2007
Author(s): Rawal, N., Parish, C., Castelo-Branco, G., Arenas, E.Author(s): Rawal, N., Parish, C., Castelo-Branco, G., Arenas, E. -
Midbrain dopaminergic neurogenesis and behavioural recovery in a salamander lesion-induced regeneration modelDevelopment
- Volume: 134
- Page(s): 2881-2887
- Year: 2007
Author(s): Parish, C.L., Beljajeva, A., Arenas, E., Simon, A.Author(s): Parish, C.L., Beljajeva, A., Arenas, E., Simon, A. -
Biomaterials for brain tissue engineeringAustralian Journal of Chemistry
- Volume: 63
- Page(s): 1143-1154
- Year: 2010
Author(s): Pettikiriarachchi, J.T.S., Parish, C.L., Shoichet, M.S., Forsythe, J.S., Nisbet, D.R.Author(s): Pettikiriarachchi, J.T.S., Parish, C.L., Shoichet, M.S., Forsythe, J.S., Nisbet, D.R. -
Liver X Receptors and Oxysterols Promote Ventral Midbrain Neurogenesis In Vivo and in Human Embryonic Stem CellsCell Stem Cell
- Volume: 5
- Page(s): 409-419
- Year: 2009
Author(s): Sacchetti, P., Sousa, K.M., Hall, A.C., Liste, I., Steffensen, K.R., Theofilopoulos, S., Parish, C.L., Hazenberg, C., Richter, L.A., Hovatta, O., Gustafsson, J.-A., Arenas, E.Author(s): Sacchetti, P., Sousa, K.M., Hall, A.C., Liste, I., Steffensen, K.R., Theofilopoulos, S., Parish, C.L., Hazenberg, C., Richter, L.A., Hovatta, O., Gustafsson, J.-A., Arenas, E. -
Dopamine D2 receptor knockout mice develop features of Parkinson diseaseAnnals of Neurology
- Volume: 66
- Page(s): 472-484
- Year: 2009
Author(s): Tinsley, R.B., Bye, C.R., Parish, C.L., Tziotis-Vais, A., George, S., Culvenor, J.G., Li, Q.-X., Masters, C.L., Finkelstein, D.I., Horne, M.K.Author(s): Tinsley, R.B., Bye, C.R., Parish, C.L., Tziotis-Vais, A., George, S., Culvenor, J.G., Li, Q.-X., Masters, C.L., Finkelstein, D.I., Horne, M.K. -
Wnt5a-treated midbrain neural stem cells improve dopamine cell replacement therapy in parkinsonian miceJournal of Clinical Investigation
- Volume: 118
- Page(s): 149-160
- Year: 2008
Author(s): Parish, C.L., Castelo-Branco, G., Rawal, N., Tonnesen, J., Sorensen, A.T., Salto, C., Kokaia, M., Lindvall, O., Arenas, E.Author(s): Parish, C.L., Castelo-Branco, G., Rawal, N., Tonnesen, J., Sorensen, A.T., Salto, C., Kokaia, M., Lindvall, O., Arenas, E. -
Quantified assessment of terminal density and innervation.Current protocols in neuroscience / editorial board, Jacqueline N. Crawley ... [et al.]
- Volume: Chapter 1
- Year: 2004
Author(s): Finkelstein, D.I., Stanic, D., Parish, C.L., Drago, J., Horne, M.K.Author(s): Finkelstein, D.I., Stanic, D., Parish, C.L., Drago, J., Horne, M.K. -
Erratum: Changes in function and ultrastructure of striatal dopaminergic terminals that regenerate following partial lesions of the Snpc (Journal of Neurochemistry (2003) 86 (329-343)Journal of Neurochemistry
- Volume: 87
- Page(s): 1056
- Year: 2003
Author(s): Stanic, D., Parish, C.L., Zhu, W.M., Krstew, E.V., Lawrence, A.J., Drago, J., Finkelstein, D.I., Horne, M.K.Author(s): Stanic, D., Parish, C.L., Zhu, W.M., Krstew, E.V., Lawrence, A.J., Drago, J., Finkelstein, D.I., Horne, M.K. -
An efficient method for the derivation of mouse embryonic stem cellsStem Cells
- Volume: 24
- Page(s): 844-849
- Year: 2006
Author(s): Bryja, V., Bonilla, S., Čajánek, L., Parish, C.L., Schwartz, C.M., Luo, Y., Rao, M.S., Arenas, E.Author(s): Bryja, V., Bonilla, S., Čajánek, L., Parish, C.L., Schwartz, C.M., Luo, Y., Rao, M.S., Arenas, E. -
Changes in function and ultrastructure of striatal dopaminergic terminals that regenerate following partial lesions of the SNpcJournal of Neurochemistry
- Volume: 86
- Page(s): 329-343
- Year: 2003
Author(s): Stanic, D., Parish, C.L., Zhu, W.M., Krstew, E.V., Lawrence, A.J., Drago, J., Finkelstein, D.I., Horne, M.K.Author(s): Stanic, D., Parish, C.L., Zhu, W.M., Krstew, E.V., Lawrence, A.J., Drago, J., Finkelstein, D.I., Horne, M.K. -
Haloperidol treatment reverses behavioural and anatomical changes in cocaine-dependent miceNeurobiology of Disease
- Volume: 19
- Page(s): 301-311
- Year: 2005
Author(s): Parish, C.L., Drago, J., Stanic, D., Borrelli, E., Finkelstein, D.I., Horne, M.K.Author(s): Parish, C.L., Drago, J., Stanic, D., Borrelli, E., Finkelstein, D.I., Horne, M.K. -
Mice lacking the α4 nicotinic receptor subunit fail to modulate dopaminergic neuronal arbors and possess impaired dopamine transporter functionMolecular Pharmacology
- Volume: 68
- Page(s): 1376-1386
- Year: 2005
Author(s): Parish, C.L., Nunan, J., Finkelstein, D.I., McNamara, F.N., Wong, J.Y., Waddington, J.L., Brown, R.M., Lawrence, A.J., Horne, M.K., Drago, J.Author(s): Parish, C.L., Nunan, J., Finkelstein, D.I., McNamara, F.N., Wong, J.Y., Waddington, J.L., Brown, R.M., Lawrence, A.J., Horne, M.K., Drago, J. -
Cripto as a target for improving embryonic stem cell-based therapy in Parkinson's diseaseStem Cells
- Volume: 23
- Page(s): 471-476
- Year: 2005
Author(s): Parish, C.L., Parisi, S., Persico, M.G., Arenas, E., Minchiotti, G.Author(s): Parish, C.L., Parisi, S., Persico, M.G., Arenas, E., Minchiotti, G. -
Stem-cell-based strategies for the treatment of parkinson's diseaseNeurodegenerative Diseases
- Volume: 4
- Page(s): 339-347
- Year: 2007
Author(s): Parish, C.L., Arenas, E.Author(s): Parish, C.L., Arenas, E. -
Organized development from human embryonic stem cells after injection into immunodeficient miceStem Cells and Development
- Volume: 13
- Page(s): 421-435
- Year: 2004
Author(s): Gertow, K., Wolbank, S., Rozell, B., Sugars, R., Andäng, M., Parish, C.L., Imreh, M.P., Wendel, M., Ährlund-Richter, L.Author(s): Gertow, K., Wolbank, S., Rozell, B., Sugars, R., Andäng, M., Parish, C.L., Imreh, M.P., Wendel, M., Ährlund-Richter, L. -
Chronic corticotropin-releasing factor type 1 receptor antagonism with antalarmin regulates the dopaminergic system of Fawn-Hooded ratsJournal of Neurochemistry
- Volume: 94
- Page(s): 1523-1534
- Year: 2005
Author(s): Lawrence, A.J., Parish, C.L., Chen, F., Lodge, D.J., Krstew, E.V., Card, K., Finkelsteinf, D.I., Horne, M.K.Author(s): Lawrence, A.J., Parish, C.L., Chen, F., Lodge, D.J., Krstew, E.V., Card, K., Finkelsteinf, D.I., Horne, M.K. -
The role of interleukin-1, interleukin-6, and glia in inducing growth of neuronal terminal arbors in miceJournal of Neuroscience
- Volume: 22
- Page(s): 8034-8041
- Year: 2002
Author(s): Parish, C.L., Finkelstein, D.I., Tripanichkul, W., Satoskar, A.R., Drago, J., Horne, M.K.Author(s): Parish, C.L., Finkelstein, D.I., Tripanichkul, W., Satoskar, A.R., Drago, J., Horne, M.K. -
The role of dopamine receptors in regulating the size of axonal arborsJournal of Neuroscience
- Volume: 21
- Page(s): 5147-5157
- Year: 2001
Author(s): Parish, C.L., Finkelstein, D.I., Drago, J., Borrelli, E., Horne, M.K.Author(s): Parish, C.L., Finkelstein, D.I., Drago, J., Borrelli, E., Horne, M.K. -
Macrophages and microglia produce local trophic gradients that stimulate axonal sprouting toward but not beyond the wound edgeMolecular and Cellular Neuroscience
- Volume: 21
- Page(s): 436-453
- Year: 2002
Author(s): Batchelor, P.E., Porritt, M.J., Martinello, P., Parish, C.L., Liberatore, G.T., Donnan, G.A., Howells, D.W.Author(s): Batchelor, P.E., Porritt, M.J., Martinello, P., Parish, C.L., Liberatore, G.T., Donnan, G.A., Howells, D.W. -
Axonal sprouting following lesions of the rat substantia nigraNeuroscience
- Volume: 97
- Page(s): 99-112
- Year: 2000
Author(s): Finkelstein, D.I., Stanic, D., Parish, C.L., Tomas, D., Dickson, K., Horne, M.K.Author(s): Finkelstein, D.I., Stanic, D., Parish, C.L., Tomas, D., Dickson, K., Horne, M.K. -
Effects of long-term treatment with dopamine receptor agonists and antagonists on terminal arbor sizeEuropean Journal of Neuroscience
- Volume: 16
- Page(s): 787-794
- Year: 2002
Author(s): Parish, C.L., Stanic, D., Drago, J., Borrelli, E., Finkelstein, D.I., Horne, M.K.Author(s): Parish, C.L., Stanic, D., Drago, J., Borrelli, E., Finkelstein, D.I., Horne, M.K.
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