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Sleep and Cognition

Our lab focuses on the role of sleep in memory, mood, emotion and neurodegenerative disease.

Current work investigates the neurobiology of the neuropeptide orexin on sleep, in particular the influences of orexin receptor antagonists on sleep quality and subsequent performance in tests of memory and emotion in animal models. This work expands into investigations of the role of the orexin system in Alzheimer’s disease and Frontotemporal dementia, and explores the potential of orexin receptor antagonists to modulate disease progression in mouse models of these diseases.

  • Location

    Florey Institute of Neuroscience and Mental Health
    30 Royal Parade

  • Research team

    Head Dr Laura Jacobson
  • Member Mr Ryan Keenan

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