Autosomal Dominant Alzheimer’s Disease

Autosomal Dominant Alzheimer’s Disease (ADAD) is a rare form of Alzheimer’s that causes memory loss and dementia in people in their 30s to 50s.

The Dominantly Inherited Alzheimer Network Trials Unit (DIAN‐TU) has launched the first prevention trial for ADAD families. The DIAN‐TU trial focuses on drugs that could potentially change the course of the disease. The trial’s goal is to determine the safety, tolerability, and effectiveness of these drugs. The DIAN‐TU trial will determine if these medications can prevent, delay, or possibly even reverse Alzheimer’s disease changes in the brain. Although there are differences between ADAD and the more common age‐associated, sporadic Alzheimer’s disease, the results of this study will have implications for future studies and treatments in sporadic Alzheimer's disease.

How You Can Help

Are you or someone you know affected by ADAD? We are currently looking for participants that have a parent or sibling who has been affected by an ADAD mutation. Please download the brochure for more information or contact Beverley Clinch.

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