Epilepsy
The Florey's Epilepsy division is a world-leading centre for epilepsy research. The division has major groups at both the Florey’s Austin and Parkville campus. The group studies mechanisms that cause epilepsy from the level of cells to the function of the whole brain. We use technologies including advanced MRI and cutting edge cellular physiology techniques to allow us to understand genetic and acquired mechanisms that give rise to epilepsy. Together with our colleagues from The University of Melbourne and across Australia we are working towards finding a cure for epilepsy.

CO-HEAD OF DIVISION

CO-HEAD OF DIVISION

Epilepsy Cognition Laboratory

HEAD OF LAB
Dr Christopher Tailby
Dr Christopher Tailby
A glimpse at our projects
- Functional neuroimaging analysis to identify brain abnormality in epilepsy.
- Artefact reduction in functional MRI.
- Functional connectivity and the human brain functional connectome.
- Functional MRI Processing Pipelines.
- Laterality of brain function.
- Morphometry.
- Quantitative voxel-based analysis of qualitative images.
- Simultaneous EEG-fMRI.
- T2 relaxometry.
Imaging and Epilepsy

HEAD OF LAB
Prof Graeme Jackson
Prof Graeme Jackson
Innate Phagocytosis Laboratory

HEAD OF LAB
Dr Ben Gu
Dr Ben Gu
A glimpse at our projects
- Search the P2X7 related biomarkers for Alzheimer’s disease.
- The nature of the P2X4 receptor.
- The role of P2X7 in a mouse model of oligodendrocyte apoptosis.
- Investigation of P2X7 mediated phagocytosis - potential therapeutic target for cancer treatment.
- Identify the transcriptional regulatory factors of the P2X7 receptor.
- How does the brain remove the excess number of neurons during development and aging.
- Identification of serum glycoproteins altering innate immunity.
- Do circulating microvesicles from patients with multiple sclerosis (MS) disrupt the blood-brain barrier (BBB)? (For Honors and MBiomedSc).
- The Role of Innate Phagocytosis in the Pathogenesis and Treatment of Alzheimer's Disease (for PhD only).
A glimpse at our projects
- “CLARITY” based glass brain imaging in health and disease.
- Neuroanatomical determinants of susceptibility in a model of genetic epilepsy.
- Multi-site patch clamp recording of cortical micro networks.
- Projects in network analysis of genetic epilepsy.
- High content automated analysis of ion channels in epilepsy.
- High density multi-electrode array recording of in vitro networks in epilepsy.
- In vivo electrophysiological analysis in mouse models of genetic epilepsy.
- MRI tractography in mouse models of genetic epilepsy: Creation of prognostic and diagnostic structural biomarkers.
- Optogenetic modulation of the area tempestas – an epilepsy hot spot.
- TUBEROUS SCLEROSIS AND EPILEPSY: USING RESECTED TISSUE TO UNDERSTAND PATHOGENESIS.
Neural Networks Laboratory

HEAD OF LAB
Dr Lucy Palmer
Dr Lucy Palmer
A glimpse at our projects
A glimpse at our projects
A glimpse at our projects
Sleep and Cognition

HEAD OF LAB
Dr Laura Jacobson
Dr Laura Jacobson
A glimpse at our projects
Traumatic Brain Injury Laboratory

HEAD OF LAB
Prof Paul McCrory
Prof Paul McCrory