The TAM family (Tyro3, Axl and Mer) of protein tyrosine kinase receptors play pivotal roles in the processes of cell survival and proliferation, modulation of the immune response, and the removal of dead cells from tissue.
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Oligodendrocyte (OL) apoptosis is among the earliest histopathological features of multiple sclerosis (MS).
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Cytokines that belong to the IL-6 family have been implicated in the maintenance of various stem cell populations.
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Neuroinflammation regulates both disease pathogenesis and repair in multiple sclerosis (MS) and is modeled in experimental autoimmune encephalomyelitis.
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The adult subventricular zone (SVZ) is a potential source of precursor cells to replace neural cells lost during demyelination.
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Enhancement of endogenous oligodendrocyte regeneration is a promising strategy for repair in chronic demyelinating diseases of the central nervous system.
Learn More“Every great advance in science has issued from a new audacity of imagination.”
