Understanding the brain requires the integration of complex neuroscience, and particularly neuroimaging datasets, collected at multiple levels of research into brain structure and function. The Neuroimaging and Neuroinformatics group is at the forefront of rapidly advancing interdisciplinary fields that develop and apply imaging techniques and approaches that are essential to advancing our understanding of the structure and function of the human nervous system.
Magnetic Resonance Imaging (MRI) is an important basic and clinical neuroscience discipline, is able to provide direct in vivo measurements of the human brain, and is able to provide novel insights into brain and mind diseases. The research projects undertaken in the Neuroimaging and Neuroinformatics Group are aimed at improving our understanding of neurodegeneration in Friedreich’s ataxia, the identification of brain areas involved in central control of cough, and the specialized function of parietal lobe brain regions for performing mental rotation and mental manipulation.
A/Prof Nellie Georgiou-Karistianis
Department of Psychology, Monash University
Longitudinal functional MRI studies of cognitive decline in pre-symptomatic Huntington’s disease
Dr Caron Chapman and Dr Mark Paine
Department of Opthamology, Royal Victorian Eye and Ear Hospital
MRI investigations in optic neuritis patients
Dr Michael Ditchfield,
Head, MRI, Royal Children’s Hospital
High field MRI studies
Prof Iven Mareels
School of Engineering, University of Melbourne
Magnetic Resonance Image and signal processing
A/Prof Peter Farrell
School of Engineering, University of Melbourne
Optimised MRI acqusition
Dr Mark Morelande
School of Engineering, University of Melbourne
Optimised MRI acquisition
A/Prof Jingxin Zhang
Monash University
MRI reconstruction and parallel imaging
Prof Stephen Gibson
National Ageing Research Institute
Studies of central pain processing in ageing and Alzheimer’s disease
Prof Lex Doyle and Dr Peter Anderson
Department of Neonatology, Royal Women’s Hospital and Royal Children’s Hospital, Melbourne
MRI assessment of neonatal brain development
Prof David Walker
Department of Physiology
Monash University
Modelling the cortical folding process using MRI
Dr Stuart Mazzone
University of Queensland
Imaging the urge to cough
Dr Ken Matsuda
Bernard O’Brien Institute of Microsurgery
Quantiative Peripheral Nerve Imaging
Dr Nigel Jones, Dr Viviane Bouillerent, Howard Ho Fung Tang, Prof Terrence O’Brien
Department of Medicine – RMH, University of Melbourne
MRI investigation of the temporal progression of epilepsy and anxiety pathologies, and the effects of intervention, in GAERS epileptic rats
Dr Sonia Davison, Dr Robin Bell, Prof Susan Davies
Department of Medicine, Alfred Hospitaland Monash University
Assessing the effects of hormonal treatments on cognition function in women
Dr Jacqueline Orian
La Trobe University
Grey matter pathology with pre-clinical murine experimental autoimmune encephalomyelitis (EAE)
Prof Ashley Bush, A/Prof David Finkelstein
Mental Health Research Institute
Manganese enhanced MRI in the APP transgenic and the ZnT3 knock-out mouse models
Dr Paul Lockhart and Ms Gabi Wilson
Murdoch Children’s Research Institute
MRI analyses the absence of Parkin co-regulated gene (Pacrg) occurrence of hydrocephalus in mouse
A/Prof Richard Weisinger
La Trobe University
MRI investigation of decreased body fat
Mr Jason Lohrey
Arcitecta
Neuroscience Informatics
Dr Ann Borda, Dr Steve Melnikoff, Mr Jared Winton and Mr Jason Chen
Victorian eResearch Strategic Initiative
Neuroscience Informatics
Prof Christopher Rowe, Prof Colin Masters and Prof David Ames
Australian Imaging Biomarkers and Lifestyle Project
Prof Sam Berkovic and Prof Ingrid Scheffer
University of Melbourne
Prof Graeme Jackson and Dr Steve Petrou
Florey Neuroscience Institutes
Prof David Reutens
University of Queensland
Prof John Mulley and Prof Josef Gecz
University of Adelaide
As part of a NHMRC Program Grant team, the investigation of the molecular basis for and brain abnormalities associated with a range of epilepsies
Prof. Geoffrey A. Donnan and A/Prof Helen Dewey
NSRI
Characterisation of the penumbra in patients with acute stroke using advanced perfusion MRI techniques
Dr Amy Brodtmann
NSRI
To establish whether arterial stenoses can cause cortical remodelling within brain regions supplied by the affected vessel
Prof. Sheena Reilly and Dr. Angela Morgan
Murdoch Children’s Research Institute
To determine the structural-functional abnormalities in children with developmental language disorders
Dr. Mark Mackay
Murdoch Children’s Research Institute
Characterisation of the ischaemic penumbra in children with stroke
Prof Stephen Davis, Dr Patricia Desmond and Dr Soren Christensen
Royal Melbourne Hospital
To develop improved perfusion MRI methods for the analysis of the MR perfusion data from patients with stroke
Prof. Iven Mareels and Dr Leigh Johnston
Department of Electrical and Electronic Engineering, University of Melbourne
Development of improved methods of measuring white matter connectivity using diffusion MRI
A/Prof. Gavin Fabinyi
Austin Health
Investigation of the efficacy of diffusion based MRI white matter fibre tracking in predicting the visual field deficits commonly experienced by patients undergoing temporal lobe neurosurgery
Dr. Olivier Salvado and Prof Stuart Crozier
CSIRO, University of Queensland
To develop methods to spatially normalise white matter fibre orientation images across subjects and perform group analyses of high angular resolution diffusion weighted MRI data
Dr Janniko Georgiadis
Department of Anatomy
University of Groningen Medical Center, Netherlands
Neuronal mechanisms underlying sexual satiety in men
Prof Peter Fox and Prof Jack Lancaster
Research Imaging Centre, University of Texas, San Antonio, USA
Neurophysiological mechanisms subserving primal emotions
A/Prof Terri Inder
Washington University, USA
Neonatal brain development
Dr Yaou (Euroasia) Liu
Department of Radiology, XuanWu Hospital, Capital Medical University,
Beijing, People’s Republic of China
Prof Zang-Hee Cho
Neuroscience Research Institute, Gachon, Korea
Prof. Leif Ostergaard
Center for Functionally Integrative Neuroscience, Århus University Hospital, Denmark
Improved methods to measure perfusion using MRI
A/Prof. Matthias van Osch
Leiden University Medical Centre, Leiden, The Netherlands.
Investigation of contrast-agent quantification issues in perfusion MRI
A/Prof. Juan Cebral
George Mason University, Virginia, USA
MRI data computational fluid dynamics modelling to develop models of vascular territories and collateral circulation of the brain
Dr. Roland Bammer
Stanford University, USA
Comparison of MRI measurements of blood flow in the arteries with those predicted using computational fluid dynamics
Dr. David Thomas
University of London, UK
Development of improved method of quantifying cerebral blood flow using arterial spin labelling
Dr. Chin-Po Lin
National Yang-Ming University, Taipei, Taiwan
To investigate MRI methods to identify white matter fibre orientations in the brain using experimental water phantoms
Dr. Torsten Baldeweg, Dr Frederique Liegeois and Dr Brigitte Vollmer
Institute of Child Heath, University College London and Karolinska Institute, Stockholm, Sweden
Combined neuropsychological and neuroimaging study of speech and language function in preterm children with perinatally acquired brain lesions
Dr. Martin King, Dr Brigitte Vollmer and Dr Samuel Groeschel
Institute of Child Heath, University College London, and Karolinska Institute, Stockholm, Sweden
Neuroimaging study of normal brain development from infancy to adulthood
Prof David Gadian, Dr WK Chong, Dr Frederique Liegeois and Prof Helen Cross
Institute of Child Heath, University College London
Functional neuroimaging studies in children with focal epilepsy
Prof Lex Doyle, Dr Peter Anderson, Prof Terrie Inder and Prof Jeff Neil
Royal Women’s Hospital, Melbourne and St Louis, USA
Determining the mechanisms leading to long term impairment in very pre-term children
“Research is the process of going up alleys to see if they are blind.”
